Reto Fiolka

Scientists at Janelia work together in multidisciplinary teams to solve challenging biological problems that are difficult to address in other research settings.

Many lab spaces at Janelia feature modular designs and natural light.

Credit: Brad Feinknopf

Occupying 689 wooded acres along the Potomac River, Janelia Farm provides a variety of services and facilities to support its diverse community of scientists and staff—inside and outside the lab.

A view of the Janelia Farm Research Campus at dusk.

Credit: Brad Feinknopf

The Janelia Farm model frees scientists of constraints commonly found in other research environments, providing access to world-class resources and a talented support staff.

Graduate scholar John Tuthill prepares a Drosophila specimen for imaging.

Credit: James Kegley

In addition to our resident scientists and fellows, we offer visiting scientists, graduate, and undergraduate candidates a range of scientific programs.

Graduate scholar Arbora Resulaj (left) and her mentor, Janelia Fellow Dmitry Rinberg (right).

Credit: James Kegley

Janelia Farm regularly hosts scientific meetings, ranging from workshops to intensive, specialized conferences. See what's coming up and visit the archive of past events.

Janelia's large auditorium seats 250 people.

Credit: Matt Staley

Janelia provides outstanding employment opportunities, at all levels.

Credit: James Kegley

Many tools developed in Janelia Farm labs are made freely available to outside researchers, while others are taking shape through collaborations with industry, academia, and government.

A virtual arena for the study of flight in insects.

Credit: James Kegley

Janelia’s sense of community comes from a core belief that people of diverse disciplines and backgrounds can accomplish great things when working with a common purpose.

Research specialist Trevor Wardill (left) and group leader Vivek Jayaraman (right).

Credit: James Kegley

Cui Lab

Associate

Contact Me

Deep tissue imaging is a challenge, since abberations and random scattering prevent the formation of a proper focus. However, a properly designed wavefront that exactly compensates all the distortions in the sample can yield an ideal focus, independent of the complexity of the scattering. This principle is known as optical phase conjugation (OPC). The question is how to find this wavefront or an approximation that can do the job.

The aim of my research is to develop microscopy techniques that can rapidly estimate complex wavefront corrections for 2 photon imaging in brain tissue.

In my previous work at Janelia, I have built a fast multi-purpose structured illumination microscope (SIM). SIM allows to double the diffraction limited resolution in all three dimensions and combined with fast cameras (sCMOS) and spatial light modulators, it can be applied to live cell imaging.

My research interests encompass microscopy, interferometry, holography, light scattering, ultrafast laser optics and liquid crystals.

Education:

2001-2006: Undergraduate studies in Mechanical Engineering, ETH Zurich,

Switzerland

2006-2009: PhD studies at the Chair of Nanotechnology, ETH Zurich, Switzerland

April 2010: Visitor at the synchrotron of the Paul Scherrer Institute in Switzerland

In my PhD thesis I worked on improving the resolution in quantitative phase microscopy and fluorescence microscopy. In 2010, I shortly worked on a project for quantitative hard X-ray tomography at the Paul Scherrer Institute in Switzerland.