@article {6893,
	title = {Bright building blocks for chemical biology.},
	journal = {ACS Chemical Biology},
	volume = {9},
	year = {2014},
	month = {2014 Mar 20},
	pages = {855-66},
	abstract = {<p>Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology. As we noted in a previous review (Lavis, L. D.; Raines, R. T. ACS Chem. Biol. 2008, 3, 142-155), the extant collection of fluorescent probes is built on a modest set of "core" scaffolds that evolved during a century of academic and industrial research. Here, we survey traditional and modern synthetic routes to small-molecule fluorophores and highlight recent biological insights attained with customized fluorescent probes. Our intent is to inspire the design and creation of new high-precision tools that empower chemical biologists.</p>
},
	issn = {1554-8937},
	doi = {10.1021/cb500078u},
	author = {Lavis, Luke D and Raines, Ronald T}
}
