@article {6938,
	title = {Rapid adaptive optical recovery of optimal resolution over large volumes.},
	journal = {Nature Methods},
	volume = {11},
	year = {2014},
	month = {2014 Apr},
	pages = {625-8},
	abstract = {<p>Using a descanned, laser-induced guide star and direct wavefront sensing, we demonstrate adaptive correction of complex optical aberrations at high numerical aperture (NA) and a 14-ms update rate. This correction permits us to compensate for the rapid spatial variation in aberration often encountered in biological specimens and to recover diffraction-limited imaging over large volumes (\&gt;240 mm per side). We applied this to image fine neuronal processes and subcellular dynamics within the zebrafish brain.</p>
},
	doi = {10.1038/nmeth.2925},
	author = {Wang, Kai and Milkie, Daniel E and Saxena, Ankur and Engerer, Peter and Misgeld, Thomas and Bronner, Marianne E. and Mumm, Jeff and Betzig, Eric}
}
