@article {5309,
	title = {Super-resolution 3D microscopy of live whole cells using structured illumination.},
	journal = {Nature Methods},
	volume = {8},
	year = {2011},
	month = {2011 Dec},
	pages = {1044-6},
	abstract = {<p>Three-dimensional (3D) structured-illumination microscopy (SIM) can double the lateral and axial resolution of a wide-field fluorescence microscope but has been too slow for live imaging. Here we apply 3D SIM to living samples and record whole cells at up to 5 s per volume for \&gt;50 time points with 120-nm lateral and 360-nm axial resolution. We demonstrate the technique by imaging microtubules in S2 cells and mitochondria in HeLa cells.</p>
},
	keywords = {Animals, Cell Line, Cell Survival, Drosophila melanogaster, Fluorescence, Hela Cells, Humans, Imaging, Microscopy, Microtubules, Mitochondria, Three-Dimensional},
	issn = {1548-7105},
	doi = {10.1038/nmeth.1734},
	author = {Shao, Lin and Kner, Peter and Rego, E Hesper and Gustafsson, Mats G L}
}
