@article {2783,
	title = {Axial CID and high pressure resonance CID in a miniature ion trap mass spectrometer using a discontinuous atmospheric pressure interface.},
	journal = {Journal of the American Society for Mass Spectrometry},
	volume = {21},
	year = {2010},
	month = {2010 Feb},
	pages = {209-14},
	abstract = {<p>Axial collision induced dissociation (CID) and high-pressure resonance CID were implemented and compared with normal low-pressure resonance CID in a miniature ion trap mass spectrometer to obtain more complete fragmentation spectra. Axial CID was realized simply by applying a potential to the discontinuous atmospheric pressure interface (DAPI) capillary without performing parent ion isolation before dissociation. High-pressure resonance CID employed a double-introduction pulse scan function, by means of which precursor ions isolated at low-pressure (\&lt;10(-3) torr) were dissociated at high-pressure (0.1 torr-1 torr) with higher excitation energy, so that tandem MS of isolated precursor ions was achieved and extensive fragmentation was obtained. A simple peptide (Leu-enkephalin) and dye molecule (rhodamine B) ionized by ESI were used to investigate both methods and compare them with normal low-pressure resonance CID.</p>
},
	issn = {1879-1123},
	doi = {10.1364/AO.50.001792},
	author = {Gao, Liang and Li, Guangtao and Cooks, R Graham}
}
