@article {2751,
	title = {Identification of genes controlled by LMX1B in E13.5 mouse limbs.},
	journal = {Developmental Dynamics: An Official Publication of the American Association of Anatomists},
	volume = {239},
	year = {2010},
	month = {2010 Aug},
	pages = {2246-55},
	abstract = {<p>During limb development, the dorsal limb mesenchyme expression of the transcription factor LMX1B is required for dorsoventral limb patterning. In mice, Lmx1b mutations result in the mirror-image duplication of ventral limb structures and loss of dorsal limb structures. Heterozygous LMX1B mutations in humans cause the Nail-Patella Syndrome characterized by limb, kidney, and eye developmental defects. We used DNA microarrays to compare the mRNAs in E13.5 mouse Lmx1b mutant and wild-type limbs. We report 14 genes that require Lmx1b for their normal expression in the dorsal limb or the restriction of their expression to the ventral limb.</p>
},
	keywords = {Animals, Body Patterning, Extremities, Gene Expression, Genes, Homeodomain Proteins, Humans, Messenger, Mice, Oligonucleotide Array Sequence Analysis, RNA, Transcription Factors},
	issn = {1097-0177},
	doi = {10.1002/dvdy.22357},
	author = {Gu, Wendy X W and Kania, Artur}
}
