@article {2155,
	title = {Phenotype clustering of breast epithelial cells in confocal images based on nuclear protein distribution analysis.},
	journal = {BMC Cell Biology},
	volume = {8 },
	year = {2007},
	month = {2007 Jul 10},
	pages = {S3},
	abstract = {<p>The distribution of chromatin-associated proteins plays a key role in directing nuclear function. Previously, we developed an image-based method to quantify the nuclear distributions of proteins and showed that these distributions depended on the phenotype of human mammary epithelial cells. Here we describe a method that creates a hierarchical tree of the given cell phenotypes and calculates the statistical significance between them, based on the clustering analysis of nuclear protein distributions.</p>
},
	keywords = {Breast, Breast Neoplasms, Cell Line, Cluster Analysis, Computer-Assisted, Confocal, Epithelial Cells, Female, Humans, Image Processing, Imaging, Microscopy, Models, Nuclear Proteins, Phenotype, Statistical, Three-Dimensional},
	issn = {1471-2121},
	doi = {10.1007/s12021-010-9090-x},
	author = {Long, Fuhui and Peng, Hanchuan and Sudar, Damir and Leli{\`e}vre, Sophie A and Knowles, David W}
}
