@article {2447,
	title = {The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster.},
	journal = {Current Biology},
	volume = {15},
	year = {2005},
	month = {2005 Oct 25},
	pages = {1796-807},
	abstract = {<p>The timely onset of metamorphosis in holometabolous insects depends on their reaching the appropriate size known as critical weight. Once critical weight is reached, juvenile hormone (JH) titers decline, resulting in the release of prothoracicotropic hormone (PTTH) at the next photoperiod gate and thereby inducing metamorphosis. How individuals determine when they have reached critical weight is unknown. We present evidence that in Drosophila, a component of the ring gland, the prothoracic gland (PG), assesses growth to determine when critical weight has been achieved.</p>
},
	keywords = {Animals, Biological, Body Weight, Developmental, Drosophila, Drosophila Proteins, Ecdysteroids, Endocrine Glands, Gene Expression Regulation, Immunoenzyme Techniques, Insect Hormones, Insulin, Larva, Metamorphosis, PTEN Phosphohydrolase},
	issn = {0960-9822},
	doi = {10.1016/j.cub.2005.09.017},
	author = {Mirth, Christen and Truman, James W and Riddiford, Lynn M}
}
