@article {1159,
	title = {The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex-specifically regulated by Sex-lethal.},
	journal = {Development},
	volume = {121},
	year = {1995},
	month = {1995 Oct},
	pages = {3245-58},
	abstract = {<p>In Drosophila dosage compensation increases the rate of transcription of the male{\textquoteright}s X chromosome and depends on four autosomal male-specific lethal genes. We have cloned the msl-2 gene and shown that MSL-2 protein is co-localized with the other three MSL proteins at hundreds of sites along the male polytene X chromosome and that this binding requires the other three MSL proteins. msl-2 encodes a protein with a putative DNA-binding domain: the RING finger. MSL-2 protein is not produced in females and sequences in both the 5{\textquoteright} and 3{\textquoteright} UTRs are important for this sex-specific regulation. Furthermore, msl-2 pre-mRNA is alternatively spliced in a Sex-lethal-dependent fashion in its 5{\textquoteright} UTR.</p>
},
	issn = {0950-1991},
	author = {Baker, B.S. and Bashaw, G.J.}
}
