@article {1178,
	title = {A mammalian mitochondrial RNA processing activity contains nucleus-encoded RNA.},
	journal = {Science},
	volume = {235},
	year = {1987},
	month = {1987 Mar 6},
	pages = {1178-84},
	abstract = {<p>Ribonuclease mitochondrial RNA processing, a site-specific endoribonuclease involved in primer RNA metabolism in mammalian mitochondria, requires an RNA component for its activity. On the basis of copurification and selective inactivation with complementary oligonucleotides, a 135-nucleotide RNA species, not encoded in the mitochondrial genome, is identified as the RNA moiety of the endoribonuclease. This finding implies transport of a nucleus-encoded RNA, essential for organelle DNA replication, to the mitochondrial matrix.</p>
},
	keywords = {Animals, Base Sequence, Cell Nucleus, Chemical Phenomena, Chemistry, Drug Resistance, Endonucleases, Enzyme Activation, Genetic Code, Humans, Mammals, Micrococcal Nuclease, Mitochondria, Oligonucleotides, Organoids, Ribonucleases, RNA, Subcellular Fractions},
	issn = {0036-8075},
	doi = {10.1101/gad.1352105},
	author = {Chang, D D and Clayton, D A}
}
