@article {2465,
	title = {Endocrine regulation of the form and function of axonal arbors during insect metamorphosis.},
	journal = {The Journal of Neuroscienc : The Official Journal of the Society for Neuroscience},
	volume = {6},
	year = {1986},
	month = {1986 Jan},
	pages = {293-9},
	abstract = {<p>By discrete manipulation of the endocrine cues that control insect metamorphosis, it has been possible to examine the mechanisms governing the growth of neural processes during development. During the transition from larva to pupa in the hawkmoth, Manduca sexta, identified sensory neurons reorganize their central projections to evoke a new behavior{\textendash}the gintrap reflex. Topical application of a juvenile hormone analog to the peripheral cell bodies of these sensory neurons during a critical period of development caused them to retain their larval commitment rather than undergo pupal development with the rest of the animal. The sensory neurons retained the larval arborization pattern within the pupal CNS and were unable to evoke the gin-trap reflex. Thus, the hormonal environment of the cell body is critical for controlling growth and synapse formation by distant axonal processes.</p>
},
	keywords = {Animal, Animals, Axons, Behavior, Biological, Cobalt, Juvenile Hormones, Larva, Lepidoptera, Metamorphosis, Moths, Neurons},
	issn = {0270-6474},
	author = {Levine, R B and Truman, J W and Linn, D and Bate, C M}
}
