@article {981,
	title = {The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P-strain-specific transposon family.},
	journal = {Cell},
	volume = {29},
	year = {1982},
	month = {1982 Jul},
	pages = {995-1004},
	abstract = {<p>We have shown previously that four of five white mutant alleles arising in P-M dysgenic hybrids result from the insertion of strongly homologous DNA sequence elements. We have named these P elements. We report that P elements are present in 30-50 copies per haploid genome in all P strains examined and apparently are missing entirely from all M strains examined, with one exception. Furthermore, members of the P family apparently transpose frequently in P-M dysgenic hybrids; chromosomes descendant from P-M dysgenic hybrids frequently show newly acquired P elements. Finally, the strain-specific breakpoint hotspots for the rearrangement of the pi 2 P X chromosome occurring in P-M dysgenic hybrids are apparently sites of residence of P elements. These observations strongly support the P factor hypothesis for the mechanistic basis of P-M hybrid dysgenesis.</p>
},
	keywords = {Base Sequence, Biological Evolution, DNA Transposable Elements, Drosophila, Female, Gene Expression Regulation, Genetic, Hybridization, Infertility, Male, Nucleic Acid, Recombination, Repetitive Sequences},
	issn = {0092-8674},
	doi = {10.1186/gb-2007-8-7-r145},
	author = {Bingham, P M and Kidwell, M G and Rubin, G M}
}
