@article {46747,
	title = {Label-free spectroscopic detection of membrane potential using stimulated Raman scattering.},
	journal = {Applied Physics Letters},
	volume = {106},
	year = {2015},
	month = {2015 Apr 27},
	pages = {173704},
	abstract = {<p>Hyperspectral stimulated Raman scattering microscopy is deployed to measure single-membrane vibrational spectrum as a function of membrane potential. Using erythrocyte ghost as a model, quantitative correlation between transmembrane potential and Raman spectral profile was found. Specifically, the ratio between the area under Raman band at \~{}2930 cm-1 and that at \~{}2850 cm-1 increased by \~{}2.6 times when the potential across the erythrocyte ghost membrane varied from +10 mV to -10 mV. Our results show the feasibility of employing stimulated Raman scattering microscopy to probe the membrane potential without labeling.</p>
},
	doi = {10.1063/1.4919104},
	author = {Liu, Bin and Lee, Hyeon Jeong and Zhang, Delong and Liao, Chien-Sheng and Ji, Na and Xia, Yuanqin and Cheng, Ji-Xin}
}
