@article {48252,
	title = {The glia of the adult Drosophila nervous system.},
	journal = {Glia},
	volume = {65},
	year = {2017},
	month = {2017 Jan 30},
	pages = {606-38},
	abstract = {<p>Glia play crucial roles in the development and homeostasis of the nervous system. While the GLIA in the Drosophila embryo have been well characterized, their study in the adult nervous system has been limited. Here, we present a detailed description of the glia in the adult nervous system, based on the analysis of some 500 glial drivers we identified within a collection of synthetic GAL4 lines. We find that glia make up \~{}10\% of the cells in the nervous system and envelop all compartments of neurons (soma, dendrites, axons) as well as the nervous system as a whole. Our morphological analysis suggests a set of simple rules governing the morphogenesis of glia and their interactions with other cells. All glial subtypes minimize contact with their glial neighbors but maximize their contact with neurons and adapt their macromorphology and micromorphology to the neuronal entities they envelop. Finally, glial cells show no obvious spatial organization or registration with neuronal entities. Our detailed description of all glial subtypes and their regional specializations, together with the powerful genetic toolkit we provide, will facilitate the functional analysis of glia in the mature nervous system. GLIA 2017.</p>
},
	issn = {1098-1136},
	doi = {10.1002/glia.23115},
	author = {Kremer, Malte C and Jung, Christophe and Batelli, Sara and Rubin, Gerald M and Gaul, Ulrike}
}
