@article {65903,
	title = {Two-parameter single-molecule analysis for measurement of chromatin mobility.},
	journal = {STAR Protocols},
	volume = {1},
	year = {2020},
	month = {2020 Dec 13},
	pages = {100223},
	abstract = {<p>This protocol provides a two-parameter analysis of single-molecule tracking (SMT) trajectories of Halo-tagged histones in living adherent cell lines and unveils a chromatin mobility landscape composed of five chromatin types, ranging from low to high mobility. When the analysis is applied to Halo-tagged, chromatin-binding proteins, it associates chromatin interaction properties with known functions in a way that previously used SMT parameters did not. For complete information on the use and execution of this protocol, please refer to Lerner et\&nbsp;al. (2020).</p>
},
	issn = {2666-1667},
	doi = {10.1016/j.xpro.2020.100223},
	author = {Lerner, Jonathan and Gomez-Garcia, Pablo Aurelio and McCarthy, Ryan L and Liu, Zhe and Lakadamyali, Melike and Zaret, Kenneth S}
}
