@article {69285,
	title = {RAL-1 signaling regulates lipid composition in .},
	journal = {MicroPubl Biol},
	volume = {2024},
	year = {2024},
	month = {2024 Feb 21},
	abstract = {<p>Signaling by the Ral small GTPase is poorly understood . animals with constitutively activated RAL-1 or deficient for the inhibitory RalGAP, HGAP-1 /2, display pale intestines. Staining with Oil Red O detected decreased intestinal lipids in the deletion mutant relative to the wild type. Constitutively activated RAL-1 decreased lipid detected by stimulated Raman scattering (SRS) microscopy, a label-free method of detecting lipid by laser excitation and detection. A signaling-deficient missense mutant for RAL-1 also displayed reduced lipid staining via SRS. We conclude that RAL-1 signaling regulates lipid homeostasis, biosynthesis or storage in live animals.</p>
},
	issn = {2578-9430},
	doi = {10.17912/micropub.biology.001054},
	author = {Wu, You and Lee, Minjung and Mutlu, A Sena and Wang, Meng and Reiner, David J}
}
