@article {70215,
	title = {Signatures of remote planning in hippocampal replay},
	journal = {bioRxiv},
	year = {2025},
	month = {2025 Dec 04},
	abstract = {<p>During brief, intermittent {\textquotedblleft}replay{\textquotedblright} events, hippocampal activity can express navigational trajectories disconnected from both when and where they originally occurred. While replay biased toward immediate future goals has been observed, there is no evidence yet linking replay to planning beyond the next action. Here, we designed a sequential spatial working memory task which required rats to utilize information across multiple temporally separated actions. Remote replay events matched the animal{\textquoteright}s future navigational choices made after completing an intervening subtask. Critically, this occurred only when the replayed information was useful for reducing memory load, consistent with it being an active process. Our findings suggest these remote replay events are a neural correlate of episodic forethought, allowing animals to use memories to plan beyond their immediate surroundings.</p>
},
	doi = {10.64898/2025.12.02.691753},
	url = {https://www.biorxiv.org/content/early/2025/12/04/2025.12.02.691753},
	author = {Lustig, Brian and Wang, Yingxue and Romani, Sandro and Pastalkova, Eva and Lee, Albert K.}
}
