@article {70428,
	title = {Reward magnitude determines reinforcement learning efficiency.},
	journal = {Science},
	volume = {392},
	year = {2026},
	month = {2026 May 21},
	pages = {eaeb0813},
	abstract = {<p>Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five behavioral paradigms in na{\"\i}ve mice. Especially large rewards could substantially improve learning efficiency through dissociable effects on within- and across-session learning and task engagement. The duration and magnitude of ventral striatal dopamine release scaled with reward sizes, and prolonged optogenetic enhancement of dopamine reward responses also reproduced much, but not all, of the benefits to learning produced by outsized rewards. These findings indicate that the reinforcement learning efficiency of animals has traditionally been underestimated and that dopamine signaling of rewards mediates task engagement in proportion to absolute reward magnitude.</p>
},
	keywords = {Animals, Behavior, Animal, Dopamine, Learning, Male, Mice, Mice, Inbred C57BL, Optogenetics, Reinforcement, Psychology, Reward, Ventral Striatum},
	issn = {1095-9203},
	doi = {10.1126/science.aeb0813},
	url = {https://doi.org/10.1126/science.aeb0813},
	author = {Gong, Sheng and Martell, Alyssa and Dudman, Joshua T and Coddington, Luke T}
}
