@article {69568,
	title = {DaCapo: a modular deep learning framework for scalable 3D image segmentation},
	journal = {arXiv},
	year = {2024},
	month = {2024 Aug 05},
	abstract = {<p>DaCapo is a specialized deep learning library tailored to expedite the training and application of existing machine learning approaches on large, near-isotropic image data. In this correspondence, we introduce DaCapo{\textquoteright}s unique features optimized for this specific domain, highlighting its modular structure, efficient experiment management tools, and scalable deployment capabilities. We discuss its potential to improve access to large-scale, isotropic image segmentation and invite the community to explore and contribute to this open-source initiative.</p>
},
	doi = {10.48550/arXiv.2408.02834},
	url = {https://doi.org/10.48550/arXiv.2408.02834},
	author = {Patton, William and Rhoades, Jeff L and Zouinkhi, Marwan and Ackerman, David G and Malin-Mayor, Caroline and Adjavon, Diane and Heinrich, Larissa and Bennett, Davis and Zubov, Yurii and Team, CellMap Project and Weigel, Aubrey and Funke, Jan}
}
@article {65030,
	title = {Membrane bending moduli of coexisting liquid phases containing transmembrane peptide.},
	journal = {Biophys J},
	volume = {114},
	year = {2018},
	month = {2018 May 08},
	pages = {2152-2164},
	abstract = {<p>A number of highly curved membranes in\&nbsp;vivo, such as epithelial cell microvilli, have the relatively high sphingolipid content associated with "raft-like" composition. Given the much lower bending energy measured for bilayers with "nonraft" low sphingomyelin and low cholesterol content, observing high curvature for presumably more rigid compositions seems counterintuitive. To understand this behavior, we measured membrane rigidity by fluctuation analysis of giant unilamellar vesicles. We found that including a transmembrane helical GWALP peptide increases the membrane bending modulus of the liquid-disordered (Ld) phase. We observed this increase at both low-cholesterol fraction and higher, more physiological cholesterol fraction. We find that simplified, commonly used Ld and liquid-ordered (Lo) phases are not representative of those that coexist. When Ld and Lo phases coexist, GWALP peptide favors the Ld phase with a partition coefficient of 3-10 depending on mixture composition. In model membranes at high cholesterol fractions, Ld phases with GWALP have greater bending moduli than the Lo phase that would coexist.</p>
},
	keywords = {Amino Acid Sequence, Biomechanical Phenomena, Cell Membrane, Cholesterol, Mechanical Phenomena, Models, Molecular, Oligopeptides, Protein Conformation, alpha-Helical},
	issn = {1542-0086},
	doi = {10.1016/j.bpj.2018.03.026},
	author = {Usery, Rebecca D and Enoki, Thais A and Wickramasinghe, Sanjula P and Nguyen, Vanessa P and Ackerman, David G and Greathouse, Denise V and Koeppe, Roger E and Barrera, Francisco N and Feigenson, Gerald W}
}
