@article {68783, title = {Modulation of calcium signaling {\textquotedblleft}on demand{\textquotedblright} to decipher the molecular mechanisms responsible for primary aldosteronism}, journal = {Archives of Cardiovascular Diseases Supplements}, volume = {15}, year = {2023}, month = {2023 May 01}, pages = {188}, abstract = {

Primary aldosteronism\ (PA) is the most frequent form of secondary hypertension. Over the past two decades, major advances have been made in our understanding of the disease with the identification of germline or somatic mutations in ion channels and pumps. These mutations enhance\ calcium signaling, the main trigger of\ aldosterone\ biosynthesis.

}, issn = {18786480}, doi = {10.1016/j.acvdsp.2023.03.021}, url = {https://doi.org/10.1016/j.acvdsp.2023.03.021}, author = {Fedlaoui, Bakhta and Cosentino, Teresa and Al Sayed, Zeina R. and Fernandes-Rosa, Fabio L. and Hulot, Jean-S{\'e}bastien and Magnus, Chris and Sternson, Scott M. and Travers-Allard, Simon and Baron, St{\'e}phanie and Giscos-Douriez, Isabelle and Zennaro, Maria Christina and Boulkroun, Sheerazed} } @article {65138, title = {Reconstruction of 1,000 projection neurons reveals new cell types and organization of long-range connectivity in the mouse brain.}, journal = {Cell}, volume = {179}, year = {2019}, month = {2019 Sep 19}, pages = {268-81}, abstract = {

Neuronal\ cell\ types\ are the nodes of neural circuits that determine the flow of information within the\ brain. Neuronal morphology, especially the shape of the axonal arbor, provides an essential descriptor of\ cell\ type and\ reveals\ how individual\ neurons\ route their output across the\ brain. Despite the importance of morphology, few\ projection\ neurons\ in the\ mouse\ brain\ have been reconstructed in their entirety. Here we present a robust and efficient platform for imaging and reconstructing complete neuronal morphologies, including axonal arbors that span substantial portions of the\ brain. We used this platform to reconstruct more than\ 1,000\ projection\ neurons\ in the motor cortex, thalamus, subiculum, and hypothalamus. Together, the reconstructed\ neurons\ constitute more than 85\ meters of axonal length and are available in a searchable online database. Axonal shapes revealed previously unknown subtypes of\ projection\ neurons\ and suggest organizational principles of\ long-range\ connectivity.

}, issn = {00928674}, doi = {10.1016/j.cell.2019.07.042}, author = {Winnubst, Johan and Bas, Erhan and Ferreira, Tiago A. and Wu, Zhuhao and Economo, Michael N. and Edson, Patrick and Arthur, Ben J. and Bruns, Christopher and Rokicki, Konrad and Schauder, David and Olbris, Donald J. and Murphy, Sean D. and Ackerman, David G. and Arshadi, Cameron and Baldwin, Perry and Blake, Regina and Elsayed, Ahmad and Hasan, Mashtura and Ramirez, Daniel and Dos Santos, Bruno and Weldon, Monet and Zafar, Amina and Dudman, Joshua T. and Gerfen, Charles R. and Hantman, Adam W. and Korff, Wyatt and Sternson, Scott M. and Spruston, Nelson and Svoboda, Karel and Chandrashekar, Jayaram} }