@article {67827,
	title = {Enhanced Photoinduced Electron Transfer Through a Tyrosine Relay in a De Novo Designed Protein Scaffold Bearing a Photoredox Unit and a Fe               <sup>II</sup>               S <sub>4</sub>               Site},
	journal = {ChemPhotoChem},
	volume = {5},
	year = {2021},
	month = {03/2021},
	pages = {665 - 668},
	abstract = {<p>Electron transfer (ET) processes in biology over long distances often proceed via a series of hops, which reduces the distance dependence of the rate of ET. The protein matrix itself can be involved in mediating ET directly through the participation of redox-active amino acids. We have designed an electron transfer chain incorporated into a de novo protein scaffold, which is capable of photoinduced intramolecular electron transfer between a photoredox unit and a FeIIS4\&nbsp;site through a tyrosine amino acid relay. The kinetics were characterized by nanosecond laser pulse photolysis and revealed that electron transfer from [RuIIIbpymal]3+\&nbsp;proceeds most efficiently via a tyrosine located \~{}16 {\r A} from Rubpymal (bpymal=1-((1-([2,2'-bipyridin]-4-yl)-1H-1,2,3-triazol-4-yl)methyl)-1H-pyrrole-2,5-dione). Removal of the tyrosine as the electron relay station results in a 20-fold decrease in the apparent rate constant for the electron transfer.</p>
},
	issn = {2367-0932},
	doi = {10.1002/cptc.v5.710.1002/cptc.202100014},
	url = {https://onlinelibrary.wiley.com/toc/23670932/5/7},
	author = {Tebo, Alison and Quaranta, Annamaria and Pecoraro, Vincent L. and Aukauloo, Ally}
}
@article {65773,
	title = {Intramolecular Photogeneration of a Tyrosine Radical in a Designed Protein},
	journal = {ChemPhotoChem},
	volume = {1},
	year = {2017},
	month = {02/2017},
	pages = {89 {\textendash} 92},
	abstract = {<p>Long-distance biological electron transfer occurs through a hopping mechanism and often involves tyrosine as a high potential intermediate, for example in the early charge separation steps during photosynthesis. Protein design allows for the development of minimal systems to study the underlying principles of complex systems. Herein, we report the development of the first ruthenium-linked designed protein for the photogeneration of a tyrosine radical by intramolecular electron transfer.</p>
},
	doi = {10.1002/cptc.201600044},
	url = {https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cptc.201600044},
	author = {Tebo, Alison G and Quaranta, Annamaria and Herrero, Christian and Pecoraro, Vincent L and Aukauloo, Ally}
}
