@article {5329,
	title = {Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.},
	journal = {Current Biology},
	volume = {22},
	year = {2012},
	month = {2012 May 8},
	pages = {743-52},
	abstract = {<p>Nociception generally evokes rapid withdrawal behavior in order to protect the tissue from harmful insults. Most nociceptive neurons responding to mechanical insults display highly branched dendrites, an anatomy shared by Caenorhabditis elegans FLP and PVD neurons, which mediate harsh touch responses. Although several primary molecular nociceptive sensors have been characterized, less is known about modulation and amplification of noxious signals within nociceptor neurons. First, we analyzed the FLP/PVD network by optogenetics and studied integration of signals from these cells in downstream interneurons. Second, we investigated which genes modulate PVD function, based on prior single-neuron mRNA profiling of PVD.</p>
},
	keywords = {Ion Channels, Neurons},
	issn = {1879-0445},
	doi = {10.1016/j.cub.2012.02.066},
	author = {Husson, Steven J and Costa, Wagner Steuer and Wabnig, Sebastian and Stirman, Jeffrey N and Watson, Joseph D and Spencer, W Clay and Akerboom, Jasper and Looger, Loren L and Treinin, Millet and Miller, David M and Lu, Hang and Gottschalk, Alexander}
}
@article {4070,
	title = {A computational statistics approach for estimating the spatial range of morphogen gradients.},
	journal = {Development},
	volume = {138},
	year = {2011},
	month = {2011 Nov},
	pages = {4867-74},
	abstract = {<p>A crucial issue in studies of morphogen gradients relates to their range: the distance over which they can act as direct regulators of cell signaling, gene expression and cell differentiation. To address this, we present a straightforward statistical framework that can be used in multiple developmental systems. We illustrate the developed approach by providing a point estimate and confidence interval for the spatial range of the graded distribution of nuclear Dorsal, a transcription factor that controls the dorsoventral pattern of the Drosophila embryo.</p>
},
	issn = {1477-9129},
	doi = {10.1242/dev.071571},
	author = {Kanodia, Jitendra S and Kim, Yoosik and Tomer, Raju and Khan, Zia and Chung, Kwanghun and Storey, John D and Lu, Hang and Keller, Philipp J and Shvartsman, Stansilas Y}
}
