@article {69289,
	title = {Carbon Nanomaterial Fluorescent Probes and Their Biological Applications},
	journal = {Chemical Reviews},
	year = {2024},
	month = {2024 Mar 13},
	abstract = {<p>Fluorescent carbon nanomaterials have broadly useful chemical and photophysical attributes that are conducive to applications in biology. In this review, we focus on materials whose photophysics allow for the use of these materials in biomedical and environmental applications, with emphasis on imaging, biosensing, and cargo delivery. The review focuses primarily on graphitic carbon nanomaterials including graphene and its derivatives, carbon nanotubes, as well as carbon dots and carbon nanohoops. Recent advances in and future prospects of these fields are discussed at depth, and where appropriate, references to reviews pertaining to older literature are provided.</p>
},
	doi = {10.1021/acs.chemrev.3c00581},
	url = {https://doi.org/10.1021/acs.chemrev.3c00581},
	author = {Krasley, Andrew T. and Li, Eugene and Galeana, Jesus M. and Bulumulla, Chandima and Beyene, Abraham G. and Demirer, Gozde S.}
}
@article {69612,
	title = {Synaptic Specializations at Dopamine Release Sites Orchestrate Efficient and Precise Neuromodulatory Signaling},
	journal = {bioRxiv},
	year = {2024},
	month = {2024 Sep 16},
	abstract = {<p>Dopamine is a key chemical neuromodulator that plays vital roles in various brain functions. Traditionally, neuromodulators like dopamine are believed to be released in a diffuse manner and are not commonly associated with synaptic structures where pre- and postsynaptic processes are closely aligned. Our findings challenge this conventional view. Using single-bouton optical measurements of dopamine release, we discovered that dopamine is predominantly released from varicosities that are juxtaposed against the processes of their target neurons. Dopamine axons specifically target neurons expressing dopamine receptors, forming synapses to release dopamine. Interestingly, varicosities that were not directly apposed to dopamine receptor-expressing processes or associated with neurons lacking dopamine receptors did not release dopamine, regardless of their vesicle content. The ultrastructure of dopamine release sites share common features of classical synapses. We further show that the dopamine released at these contact sites induces a precise, dopamine-gated biochemical response in the target processes. Our results indicate that dopamine release sites share key characteristics of conventional synapses that enable relatively precise and efficient neuromodulation of their targets.</p>
},
	doi = {10.1101/2024.09.16.613338},
	url = {https://doi.org/10.1101/2024.09.16.613338},
	author = {Bulumulla, Chandima and Walpita, Deepika and Iyer, Nirmala and Eddison, Mark and Patel, Ronak and Alcor, Damien and Ackerman, David and Beyene, Abraham G}
}
