@article {6445,
	title = {Mapping a sensory-motor network onto a structural and functional ground plan in the hindbrain.},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {108},
	year = {2011},
	month = {2011 Jan 18},
	pages = {1170-5},
	abstract = {<p>The hindbrain of larval zebrafish contains a relatively simple ground plan in which the neurons throughout it are arranged into stripes that represent broad neuronal classes that differ in transmitter identity, morphology, and transcription factor expression. Within the stripes, neurons are stacked continuously according to age as well as structural and functional properties, such as axonal extent, input resistance, and the speed at which they are recruited during movements. Here we address the question of how particular networks among the many different sensory-motor networks in hindbrain arise from such an orderly plan. We use a combination of transgenic lines and pairwise patch recording to identify excitatory and inhibitory interneurons in the hindbrain network for escape behaviors initiated by the Mauthner cell. We map this network onto the ground plan to show that an individual hindbrain network is built by drawing components in predictable ways from the underlying broad patterning of cell types stacked within stripes according to their age and structural and functional properties. Many different specialized hindbrain networks may arise similarly from a simple early patterning.</p>
},
	keywords = {Animals, Body Patterning, Brain Mapping, Computer-Assisted, Electrophysiology, Escape Reaction, Genetically Modified, Image Processing, Immunohistochemistry, Interneurons, Larva, Nerve Net, Patch-Clamp Techniques, Psychomotor Performance, Rhombencephalon, Zebrafish},
	issn = {1091-6490},
	doi = {10.1073/pnas.1012189108},
	author = {Koyama, Minoru and Kinkhabwala, Amina and Satou, Chie and Higashijima, Shin-Ichi and Fetcho, Joseph}
}
@article {6444,
	title = {A structural and functional ground plan for neurons in the hindbrain of zebrafish.},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {108},
	year = {2011},
	month = {2011 Jan 18},
	pages = {1164-9},
	abstract = {<p>The vertebrate hindbrain contains various sensory-motor networks controlling movements of the eyes, jaw, head, and body. Here we show that stripes of neurons with shared neurotransmitter phenotype that extend throughout the hindbrain of young zebrafish reflect a broad underlying structural and functional patterning. The neurotransmitter stripes contain cell types with shared gross morphologies and transcription factor markers. Neurons within a stripe are stacked systematically by extent and location of axonal projections, input resistance, and age, and are recruited along the axis of the stripe during behavior. The implication of this pattern is that the many networks in hindbrain are constructed from a series of neuronal components organized into stripes that are ordered from top to bottom according to a neuron{\textquoteright}s age, structural and functional properties, and behavioral roles. This simple organization probably forms a foundation for the construction of the networks underlying the many behaviors produced by the hindbrain.</p>
},
	keywords = {Age Factors, Animals, Body Patterning, Calcium, Confocal, Electrophysiology, Genetically Modified, Interneurons, Microscopy, Models, Nerve Net, Neurological, Neurotransmitter Agents, Rhombencephalon, Zebrafish},
	issn = {1091-6490},
	doi = {10.1073/pnas.1012185108},
	author = {Kinkhabwala, Amina and Riley, Michael and Koyama, Minoru and Monen, Joost and Satou, Chie and Kimura, Yukiko and Higashijima, Shin-Ichi and Fetcho, Joseph}
}
