@article {49413,
	title = {Topographic precision in sensory and motor corticostriatal projections varies across cell type and cortical area.},
	journal = {Nature Communications},
	volume = {9},
	year = {2018},
	month = {2018 Sep 03},
	pages = {3549},
	abstract = {<p>The striatum shows general topographic organization and regional differences in behavioral functions. How corticostriatal topography differs across cortical areas and cell types to support these distinct functions is unclear. This study contrasted corticostriatal projections from two layer 5 cell types, intratelencephalic (IT-type) and pyramidal tract (PT-type) neurons, using viral vectors expressing fluorescent reporters in Cre-driver mice. Corticostriatal projections from sensory and motor cortex are somatotopic, with a decreasing topographic specificity as injection sites move from sensory to motor and frontal areas. Topographic organization differs between IT-type and PT-type neurons, including injections in the same site, with IT-type neurons having higher topographic stereotypy than PT-type neurons. Furthermore, IT-type projections from interconnected cortical areas have stronger correlations in corticostriatal targeting than PT-type projections do. As predicted by a longstanding model, corticostriatal projections of interconnected cortical areas form parallel circuits in the basal ganglia.</p>
},
	issn = {2041-1723},
	doi = {10.1038/s41467-018-05780-7},
	author = {Hooks, Bryan M and Papale, Andrew E and Paletzki, Ronald F and Feroze, Muhammad W and Eastwood, Brian S and Couey, Jonathan J and Winnubst, Johan and Chandrashekar, Jayaram and Gerfen, Charles R}
}
@article {1768,
	title = {The taste of carbonation.},
	journal = {Science},
	volume = {326},
	year = {2009},
	month = {2009 Oct 16},
	pages = {443-5},
	abstract = {<p>Carbonated beverages are commonly available and immensely popular, but little is known about the cellular and molecular mechanisms underlying the perception of carbonation in the mouth. In mammals, carbonation elicits both somatosensory and chemosensory responses, including activation of taste neurons. We have identified the cellular and molecular substrates for the taste of carbonation. By targeted genetic ablation and the silencing of synapses in defined populations of taste receptor cells, we demonstrated that the sour-sensing cells act as the taste sensors for carbonation, and showed that carbonic anhydrase 4, a glycosylphosphatidylinositol-anchored enzyme, functions as the principal CO2 taste sensor. Together, these studies reveal the basis of the taste of carbonation as well as the contribution of taste cells in the orosensory response to CO2.</p>
},
	keywords = {Action Potentials, Animals, Benzolamide, Bicarbonates, Calcium Channels, Carbon Dioxide, Carbonated Beverages, Carbonic Anhydrase Inhibitors, Carbonic Anhydrase IV, Carbonic Anhydrases, Cell Surface, Chorda Tympani Nerve, Gene Expression Profiling, Mice, Protons, Receptors, Taste, Taste Buds, Taste Perception, Transgenic},
	issn = {1095-9203},
	doi = {10.1126/science.1174601},
	author = {Chandrashekar, Jayaram and Yarmolinsky, David and von Buchholtz, Lars and Oka, Yuki and Sly, William and Ryba, Nicholas J P and Zuker, Charles S}
}
