@article {4294,
	title = {Distinct representations and theta dynamics in dorsal and ventral hippocampus.},
	journal = {The Journal of Neuroscience: The Official Journal of the Society for Neuroscience},
	volume = {30},
	year = {2010},
	month = {2010 Feb 3},
	pages = {1777-87},
	abstract = {<p>Although anatomical, lesion, and imaging studies of the hippocampus indicate qualitatively different information processing along its septo-temporal axis, physiological mechanisms supporting such distinction are missing. We found fundamental differences between the dorsal (dCA3) and the ventral-most parts (vCA3) of the hippocampus in both environmental representation and temporal dynamics. Discrete place fields of dCA3 neurons evenly covered all parts of the testing environments. In contrast, vCA3 neurons (1) rarely showed continuous two-dimensional place fields, (2) differentiated open and closed arms of a radial maze, and (3) discharged similar firing patterns with respect to the goals, both on multiple arms of a radial maze and during opposite journeys in a zigzag maze. In addition, theta power and the fraction of theta-rhythmic neurons were substantially reduced in the ventral compared with dorsal hippocampus. We hypothesize that the spatial representation in the septo-temporal axis of the hippocampus is progressively decreased. This change is paralleled with a reduction of theta rhythm and an increased representation of nonspatial information.</p>
},
	keywords = {Animals, Hippocampus, Long-Evans, Male, Maze Learning, Neurons, Rats, Space Perception, Theta Rhythm},
	issn = {1529-2401},
	doi = {10.1523/JNEUROSCI.4681-09.2010},
	author = {Royer, S{\'e}bastien and Sirota, Anton and Patel, Jagdish and Buzs{\'a}ki, Gy{\"o}rgy}
}
@article {2343,
	title = {Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop.},
	journal = {Neuron},
	volume = {64},
	year = {2009},
	month = {2009 Oct 29},
	pages = {267-80},
	abstract = {<p>Theta oscillations are believed to play an important role in the coordination of neuronal firing in the entorhinal (EC)-hippocampal system but the underlying mechanisms are not known. We simultaneously recorded from neurons in multiple regions of the EC-hippocampal loop and examined their temporal relationships. Theta-coordinated synchronous spiking of EC neuronal populations predicted the timing of current sinks in target layers in the hippocampus. However, the temporal delays between population activities in successive anatomical stages were longer (typically by a half theta cycle) than expected from axon conduction velocities and passive synaptic integration of feed-forward excitatory inputs. We hypothesize that the temporal windows set by the theta cycles allow for local circuit interactions and thus a considerable degree of computational independence in subdivisions of the EC-hippocampal loop.</p>
},
	keywords = {Action Potentials, Animals, Electric Stimulation, Entorhinal Cortex, Hippocampus, Long-Evans, Long-Term Potentiation, Male, Models, Movement, Nerve Net, Neural Inhibition, Neural Pathways, Neurological, Neurons, Patch-Clamp Techniques, Rats, Reaction Time, Synaptic Transmission, Theta Rhythm},
	issn = {1097-4199},
	doi = {10.1523/JNEUROSCI.3773-10.2011},
	author = {Mizuseki, Kenji and Sirota, Anton and Pastalkova, Eva and Buzs{\'a}ki, Gy{\"o}rgy}
}
