@article {47083,
	title = {Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0.},
	journal = {Journal of Structural Biology},
	year = {2015},
	month = {2015 Aug 28},
	abstract = {<p>The K2 Summit camera was initially the only commercially available direct electron detection camera that was optimized for high-speed counting of primary electrons and was also the only one that implemented centroiding so that the resolution of the camera can be extended beyond the Nyquist limit set by the physical pixel size. In this study, we used well-characterized two-dimensional crystals of the membrane protein aquaporin-0 to characterize the performance of the camera below and beyond the physical Nyquist limit and to measure the influence of electron dose rate on image amplitudes and phases.</p>
},
	issn = {1095-8657},
	doi = {10.1016/j.jsb.2015.08.015},
	author = {Chiu, Po-Lin and Li, Xueming and Li, Zongli and Beckett, Brian and Brilot, Axel F and Grigorieff, Nikolaus and Agard, David A and Cheng, Yifan and Walz, Thomas}
}
@article {6338,
	title = {GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors.},
	journal = {Journal of Structural Biology},
	volume = {172},
	year = {2010},
	month = {2010 Dec},
	pages = {407-12},
	abstract = {<p>Among all the factors that determine the resolution of a 3D reconstruction by single particle electron cryo-microscopy (cryoEM), the number of particle images used in the dataset plays a major role. More images generally yield better resolution, assuming the imaged protein complex is conformationally and compositionally homogeneous. To facilitate processing of very large datasets, we modified the computer program, FREALIGN, to execute the computationally most intensive procedures on Graphics Processing Units (GPUs). Using the modified program, the execution speed increased between 10 and 240-fold depending on the task performed by FREALIGN. Here we report the steps necessary to parallelize critical FREALIGN subroutines and evaluate its performance on computers with multiple GPUs.</p>
},
	keywords = {Computer-Assisted, Cryoelectron Microscopy, Image Processing, Imaging, Three-Dimensional},
	issn = {1095-8657},
	doi = {10.1016/j.jsb.2010.06.010},
	author = {Li, Xueming and Grigorieff, Nikolaus and Cheng, Yifan}
}
