@article {6898,
	title = {Making Drosophila lineage-restricted drivers via patterned recombination in neuroblasts.},
	journal = {Nature Neuroscience},
	volume = {17},
	year = {2014},
	month = {2014 Apr},
	pages = {631-7},
	abstract = {<p>The Drosophila cerebrum originates from about 100 neuroblasts per hemisphere, with each neuroblast producing a characteristic set of neurons. Neurons from a neuroblast are often so diverse that many neuron types remain unexplored. We developed new genetic tools that target neuroblasts and their diverse descendants, increasing our ability to study fly brain structure and development. Common enhancer-based drivers label neurons on the basis of terminal identities rather than origins, which provides limited labeling in the heterogeneous neuronal lineages. We successfully converted conventional drivers that are temporarily expressed in neuroblasts, into drivers expressed in all subsequent neuroblast progeny. One technique involves immortalizing GAL4 expression in neuroblasts and their descendants. Another depends on loss of the GAL4 repressor, GAL80, from neuroblasts during early neurogenesis. Furthermore, we expanded the diversity of MARCM-based reagents and established another site-specific mitotic recombination system. Our transgenic tools can be combined to map individual neurons in specific lineages of various genotypes.</p>
},
	issn = {1546-1726},
	doi = {10.1038/nn.3654},
	author = {Awasaki, Takeshi and Kao, Chih-Fei and Lee, Ying-Jou and Yang, Ching-Po and Huang, Yaling and Pfeiffer, Barret D and Luan, Haojiang and Jing, Xiaotang and Huang, Yu-Fen and He, Yisheng and Schroeder, Mark David and Kuzin, Alexander and Brody, Thomas and Zugates, Christopher T and Odenwald, Ward F and Lee, Tzumin}
}
@article {4486,
	title = {Use of a Drosophila genome-wide conserved sequence database to identify functionally related cis-regulatory enhancers.},
	journal = {Developmental Dynamics: An Official Publication of the American Association of Anatomists},
	volume = {241},
	year = {2012},
	month = {2012 Jan},
	pages = {169-89},
	abstract = {<p>Phylogenetic footprinting has revealed that cis-regulatory enhancers consist of conserved DNA sequence clusters (CSCs). Currently, there is no systematic approach for enhancer discovery and analysis that takes full-advantage of the sequence information within enhancer CSCs.</p>
},
	issn = {1097-0177},
	doi = {10.1002/dvdy.22728},
	author = {Brody, Thomas and Yavatkar, Amarendra S and Kuzin, Alexander and Kundu, Mukta and Tyson, Leonard J and Ross, Jermaine and Lin, Tzu-Yang and Lee, Chi-Hon and Awasaki, Takeshi and Lee, Tzumin and Odenwald, Ward F}
}
