@article {1141,
	title = {The regulation of the Drosophila msl-2 gene reveals a function for sex-lethal in translational control.},
	journal = {Cell},
	volume = {89},
	year = {1997},
	month = {1997 May 30},
	pages = {789-98},
	abstract = {<p>In Drosophila, dosage compensation occurs by increasing the transcription of the single male X chromosome. Four trans-acting factors encoded by the male-specific lethal genes are required for this process. Dosage compensation is restricted to males by the splicing regulator Sex-lethal, which functions to prevent the production of the MSL-2 protein in females by an unknown mechanism. In this report, we provide evidence that Sex-lethal acts synergistically through sequences in both the 5{\textquoteright} and 3{\textquoteright} untranslated regions of MSL-2 to mediate repression. We also provide evidence that the repression of MSL-2 is directly regulated by Sex-lethal at the level of translation.</p>
},
	issn = {0092-8674},
	author = {Baker, B.S. and Bashaw, G.J.}
}
@article {1159,
	title = {The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex-specifically regulated by Sex-lethal.},
	journal = {Development},
	volume = {121},
	year = {1995},
	month = {1995 Oct},
	pages = {3245-58},
	abstract = {<p>In Drosophila dosage compensation increases the rate of transcription of the male{\textquoteright}s X chromosome and depends on four autosomal male-specific lethal genes. We have cloned the msl-2 gene and shown that MSL-2 protein is co-localized with the other three MSL proteins at hundreds of sites along the male polytene X chromosome and that this binding requires the other three MSL proteins. msl-2 encodes a protein with a putative DNA-binding domain: the RING finger. MSL-2 protein is not produced in females and sequences in both the 5{\textquoteright} and 3{\textquoteright} UTRs are important for this sex-specific regulation. Furthermore, msl-2 pre-mRNA is alternatively spliced in a Sex-lethal-dependent fashion in its 5{\textquoteright} UTR.</p>
},
	issn = {0950-1991},
	author = {Baker, B.S. and Bashaw, G.J.}
}
