@article {47178,
	title = {Dendritic integration: 60 years of progress.},
	journal = {Nature Neuroscience},
	volume = {18},
	year = {2015},
	month = {2015 Dec},
	pages = {1713-21},
	abstract = {<p>Understanding how individual neurons integrate the thousands of synaptic inputs they receive is critical to understanding how the brain works. Modeling studies in silico and experimental work in vitro, dating back more than half a century, have revealed that neurons can perform a variety of different passive and active forms of synaptic integration on their inputs. But how are synaptic inputs integrated in the intact brain? With the development of new techniques, this question has recently received substantial attention, with new findings suggesting that many of the forms of synaptic integration observed in vitro also occur in vivo, including in awake animals. Here we review six decades of progress, which collectively highlights the complex ways that single neurons integrate their inputs, emphasizing the critical role of dendrites in information processing in the brain.</p>
},
	issn = {1546-1726},
	doi = {10.1038/nn.4157},
	author = {Stuart, Greg J and Spruston, Nelson}
}
@article {45891,
	title = {Dendritic patch-clamp recording.},
	journal = {Nature Protocols},
	volume = {1},
	year = {2006},
	month = {2006},
	pages = {1235-47},
	abstract = {<p>The patch-clamp technique allows investigation of the electrical excitability of neurons and the functional properties and densities of ion channels. Most patch-clamp recordings from neurons have been made from the soma, the largest structure of individual neurons, while their dendrites, which form the majority of the surface area and receive most of the synaptic input, have been relatively neglected. This protocol describes techniques for recording from the dendrites of neurons in brain slices under direct visual control. Although the basic technique is similar to that used for somatic patching, we describe refinements and optimizations of slice quality, microscope optics, setup stability and electrode approach that are required for maximizing the success rate for dendritic recordings. Using this approach, all configurations of the patch-clamp technique (cell-attached, inside-out, whole-cell, outside-out and perforated patch) can be achieved, even for relatively distal dendrites, and simultaneous multiple-electrode dendritic recordings are also possible. The protocol--from the beginning of slice preparation to the end of the first successful recording--can be completed in 3 h.</p>
},
	keywords = {Dendrites, Patch-Clamp Techniques},
	issn = {1750-2799},
	doi = {10.1038/nprot.2006.164},
	author = {Davie, Jenny T and Kole, Maarten H P and Letzkus, Johannes J and Rancz, Ede A and Spruston, Nelson and Stuart, Greg J and H{\"a}usser, Michael}
}
