@article {65212,
	title = {Interactions between Dpr11 and DIP-γ control selection of amacrine neurons in  color vision circuits.},
	journal = {eLife},
	volume = {8},
	year = {2019},
	month = {2019 Nov 06},
	abstract = {<p>R7 UV photoreceptors (PRs) are divided into yellow (y) and pale (p) subtypes. yR7 PRs express the Dpr11 cell surface protein and are presynaptic to Dm8 amacrine neurons (yDm8) that express Dpr11{\textquoteright}s binding partner DIP-g, while pR7 PRs synapse onto DIP-g-negative pDm8. Dpr11 and DIP-g expression patterns define {\textquoteright}yellow{\textquoteright} and {\textquoteright}pale{\textquoteright} color vision circuits. We examined Dm8 neurons in these circuits by electron microscopic reconstruction and expansion microscopy. and mutations affect the morphologies of yDm8 distal ({\textquoteright}home column{\textquoteright}) dendrites. yDm8 neurons are generated in excess during development and compete for presynaptic yR7 PRs, and interactions between Dpr11 and DIP-g are required for yDm8 survival. These interactions also allow yDm8 neurons to select yR7 PRs as their appropriate home column partners. yDm8 and pDm8 neurons do not normally compete for survival signals or R7 partners, but can be forced to do so by manipulation of R7 subtype fate.</p>
},
	issn = {2050-084X},
	doi = {10.7554/eLife.48935},
	author = {Menon, Kaushiki P and Kulkarni, Vivek and Takemura, Shin-ya and Anaya, Michael and Zinn, Kai}
}
@article {47237,
	title = {Ig superfamily ligand and receptor pairs expressed in synaptic partners in Drosophila.},
	journal = {Cell},
	volume = {163},
	year = {2015},
	month = {2015 Dec 17},
	pages = {1756-69},
	abstract = {<p>Information processing relies on precise patterns of synapses between neurons. The cellular recognition mechanisms regulating this specificity are poorly understood. In the medulla of the Drosophila visual system, different neurons form synaptic connections in different layers. Here, we sought to identify candidate cell recognition molecules underlying this specificity. Using RNA sequencing (RNA-seq), we show that neurons with different synaptic specificities express unique combinations of mRNAs encoding hundreds of cell surface and secreted proteins. Using RNA-seq and protein tagging, we demonstrate that 21 paralogs of the Dpr family, a subclass of immunoglobulin (Ig)-domain containing proteins, are expressed in unique combinations in homologous neurons with different layer-specific synaptic connections. Dpr interacting proteins (DIPs), comprising nine paralogs of another subclass of Ig-containing proteins, are expressed in a complementary layer-specific fashion in a subset of synaptic partners. We propose that pairs of Dpr/DIP paralogs contribute to layer-specific patterns of synaptic connectivity.</p>
},
	issn = {1097-4172},
	doi = {10.1016/j.cell.2015.11.021},
	author = {Tan, Liming and Zhang, Kelvin Xi and Pecot, Matthew Y and Nagarkar-Jaiswal, Sonal and Lee, Pei-Tseng and Takemura, Shin-ya and McEwen, Jason M and Nern, Aljoscha and Xu, Shuwa and Tadros, Wael and Chen, Zhenqing and Zinn, Kai and Bellen, Hugo J and Morey, Marta and Zipursky, S Lawrence}
}
