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    Atalanta plasmid technology
    Overview: Next-gen DNA plasmids (pJAT series) for CRISPR-Cas9 genome modification using homology-directed repair (HDR)—originally developed for Drosophila,...
    Tools
    BAPTA-JF: Bright and Targetable Ca²⁺ Indicators
    Overview BAPTA-JF indicators merge the superior properties of the Janelia Fluor® dyes, the Ca²⁺ sensitivity of BAPTA, and the genetic targeting...
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    Biotin-Janelia Fluor® Conjugates
    Overview  Biotin-Janelia Fluor® conjugates are cell-permeable, fluorescent ligands designed for affinity purification using the HaloTag platform with easy confirmation using imaging. Drug-JF...
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    Bright, Photoactivatable (PA) Janelia Fluor® Dyes for Super-Resolution Imaging
    Overview Photoactivatable versions of Janelia Fluor® dyes combine the brightness and photostability of this small-molecule fluorophore platform with the spatial and temporal control of...
    Tools
    CaMPARI 2.0
    CaMPARI (Calcium Modulated Photoactivatable Ratiometric Integrator) is a photoconvertible protein construct that enables imaging of the integrated calcium activity of large populations of cells...
    Tools
    CASFISH: DNA labeling with CRISPR/Cas9
    Genomic DNA in cells is highly folded and organized in three dimensions. Detection and visualization of genomic DNA are widely accomplished by using various fluorescence in situ...
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    cycleHCR: spatial mapping of RNA and Proteins
    Mapping the locations of RNA in cells and tissues is a valuable technique in biomedical research for understanding fundamental principles and developing assays. Several...
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    Dyes with a Universal Coumarin Switch for Super-Resolution Microscopy
    Overview A versatile platform enabling the construction of dyes for super-resolution imaging by coupling a coumarin auxiliary to rhodamine dyes. Dyes can be tuned to be either photochromic, with...
    Tools
    FLInChR
    FLInChR is an engineered variant of a light-gated opsin, Channelrhodopsin, that functions as a potent optical inhibitor of neuronal activity.  Fusion to the ‘leader’ sequence results in...
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    Glucose Sensor
    Inventors at Howard Hughes Medical Center's Janelia Research Campus have developed a strategy for creating genetically encoded, intensity-based fluorescent sensors and an associated unique set of...