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19 Results
Showing 1-10 of 19 resultsYour Criteria:
Tools
Atalanta plasmid technology
The Atalanta technology is a significant genetic engineering advancement, simplifying cloning and improving the efficiency of CRISPR-Cas9 induced homology-directed repair (HDR) for genome...
Tools
CaMPARI 2.0
CaMPARI (Calcium Modulated Photoactivatable Ratiometric Integrator) is a photoconvertible protein construct that enables imaging of the integrated calcium activity of large populations of cells...
Tools
CASFISH: DNA labeling with CRISPR/Cas9
Genomic DNA in cells is highly folded and organized in three dimensions. Detection and visualization of genomic DNA are widely accomplished by using various fluorescence in situ...
Tools
FLInChR
FLInChR is an engineered variant of a light-gated opsin, Channelrhodopsin, that functions as a potent optical inhibitor of neuronal activity. Fusion to the ‘leader’ sequence results in...
Tools
Glucose Sensor
Inventors at Howard Hughes Medical Center's Janelia Research Campus have developed a strategy for creating genetically encoded, intensity-based fluorescent sensors and an associated unique set of...
Tools
iATPSnFR2
The iATPSnFR2 is a next-generation ATP sensor that offers significant improvements over its predecessor, iATPSnFR1, for real-time tracking of ATP levels within subcellular compartments. By...
Tools
iGABASnFR2
iGABASnFR2 is the current (2022) generation of GABA-Sensing Fluorescent Reporters developed at HHMI's Janelia Research Campus. Other sensor technologies such as SF-iGluSnFR, jGCaMP8, and...
Tools
iGluSnFR3
iGluSnFR3 is the current (2022) generation of Glutamate-Sensing Fluorescent Reporters developed at HHMI's Janelia Research Campus to image the most abundant neurotransmitter in the mammal...
Tools
Janelia Fluor® Dyes
Bright and photostable fluorescent labels are critical tools for the life sciences. A key determinant of fluorophore performance is the quantum yield (QY); dyes with improved QY values are...
Tools
jASAP voltage indicators
Progress in neuroscience demands the ability to record electrical activity optically in specifically tagged neurons in behaving animals. With that in mind, GENIE Project's accomplished researchers...