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17 Results

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    Reconstructions of Aβ(1-40) amyloid fibrils
    Abstract Amyloid fibrils characterize a diverse group of human diseases that includes Alzheimer's disease, Creutzfeldt-Jakob and type II diabetes. Alzheimer's amyloid fibrils consist of amyloid-...
    Rotavirus Double-Layered Particle CryoEM Images
    Abstract Electron cryomicroscopy (cryo-EM) yields images of macromolecular assemblies and their components, from which 3D structures can be determined, by using an image processing method...
    Rotavirus Triple-Layered Particle CryoEM Images
    Abstract Non-enveloped viruses of different types have evolved distinct mechanisms for penetrating a cellular membrane during infection. Rotavirus penetration appears to occur by a process...
    Rotavirus VP7 Recoated Particle CryoEM Images
    Abstract Rotaviruses, major causes of childhood gastroenteritis, are nonenveloped, icosahedral particles with double-strand RNA genomes. By the use of electron cryomicroscopy and single-particle...
    Shaker Voltage-Gated Potassium Channel CryoEM Image
    Abstract The voltage-gated potassium channel Shaker from Drosophila consists of a tetramer of identical subunits, each containing six transmembrane segments. The atomic structure of a bacterial...
    Synthetic 70S ribosome datasets
    Abstract We describe an implementation of maximum likelihood classification for single particle electron cryo-microscopy that is based on the FREALIGN software. Particle alignment parameters are...
    TMV in Ice - Micrographs
    Abstract The treatment of helical objects as a string of single particles has become an established technique to resolve their three-dimensional (3D) structure using electron cryo-microscopy. It...