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1 Janelia Publications
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Sternson Lab
06/15/10 |
Automatic reconstruction of 3D neuron structures using a graph-augmented deformable model.
Bioinformatics. 2010 Jun 15;26:i38-46. doi: 10.1093/bioinformatics/btq212
Digital reconstruction of 3D neuron structures is an important step toward reverse engineering the wiring and functions of a brain. However, despite a number of existing studies, this task is still challenging, especially when a 3D microscopic image has low single-to-noise ratio and discontinued segments of neurite patterns.