Application deadlines vary by meeting. See descriptions for more details.
Viruses are critical reagents for many biological experiments. In model organisms, they complement the use of transgenics and enable otherwise-impossible functionalities, such as targeted retrograde tracing. In non-model systems, they are often the only option for genetic access to cell types. In humans, they represent by far the greatest hope for gene therapy. Although there are many viral reagents to choose from, nearly all are very small modifications of the naturally occurring serovars. As such, their properties are optimized for the virus’s lifecycle rather than for experimental purposes in the lab or medical uses in humans.
Combined protein & genetic engineering represents the best opportunity to: 1) optimize these critical reagents for purposes for which they are already suitable but sub-optimal, and 2) engineer entirely new functionality into them. This meeting will bring together world experts in the fields of structural biology, protein engineering, genetic engineering, neuroscience, non-model organisms, gene therapy and virology to assemble a first-in-class conference on cutting-edge strategies for viral engineering. This is the future for next-generation viral tools & gene therapy vectors, and Janelia is excited to lead the way.
Application deadline: May 24, 2019 (11:59 p.m. ET)
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A follow up to the first meeting at Janelia in 2017, we will again bring together leading scientists working on emerging new concepts in cell biology that are important for neuron and neural circuit function. Presentations will cover topics such as emerging areas of cell biology, new imaging tools for examining the function of proteins at the subcellular level as well as cutting edge work by investigators working at the interface of cell and neuronal biology.
Application deadline: May 31, 2019 (11:59 p.m. ET)
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Janelia’s first “Women in Computational Biology” conference will showcase extraordinary research being done by women in this traditionally male-dominated field. Although small in size (~60 people), the conference will be thematically broad, with presentations and discussions on the application of computer science, mathematics and physics to cellular and molecular biology, evolutionary biology, genomics, neuroscience and image analysis. A Program Committee of six field leaders have hand-selected the invited speakers for their particular sessions and will help the organizers shape the program. A full list of program chairs and invitees is included below.
The intimate nature of Janelia conferences offers an ideal forum for attendees to network and build collaborations. Participants in this unique and exciting meeting will include women working in computational biology, as well as those of any gender who are committed to advancing or promoting the accomplishments of women in computational biology.
While presenters will identify primarily as female, all genders and those who are non-binary are welcome to apply.
Application Deadline EXTENDED to June 28, 2019 (11:59 p.m. EST)
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The genetic tractability and expansive circuit mapping toolkit of Drosophila provide an ideal model system for studying sleep and other complex behaviors. Fly sleep has been shown to follow a circadian pattern and display many of the fundamental features of mammalian sleep, including homeostatic control. Over the last decade, many cellular and molecular components controlling Drosophila sleep regulation and function have been described. This small conference will bring together experts in the field to discuss the latest advances toward a comprehensive mechanistic understanding of fly sleep. For perspective, we will also include special talks on sleep behavior in various other model systems.
Application deadline: June 28, 2019 (11:59 p.m. ET)
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Olfactory navigation is required for the survival of virtually all living creatures from unicellular organisms to mammals. This conference will focus on olfaction and spatial orientation as a unifying theme across organisms with different viewpoints: mechanistic, computational and evolutionary. We will examine how model organisms, with distinct sensory capabilities and constraints have evolved to solve this problem. From a comparative perspective, we will seek to extract fundamental principles related to the detection of (noisy) sensory stimuli and its conversion into goal-directed responses. We will also examine the modulatory effects of internal states and learning on sensorimotor control. We anticipate that control mechanisms directing orientation will be relevant to the study of sensory systems other than olfaction. Such mechanisms should also represent a source of inspiration to engineer new technologies.
The conference will tackle three challenges. The first pertains to neural mechanisms that underlie specific sensorimotor functions (filtering of noise, decision-making, etc.). Moving down from sensors to control circuits, we will discuss our understanding of the emergence of action selection from the activity of neural circuits. The second challenge will be more technical. Recently significant technological progresses have been made by mapping neural circuits in connectivity diagrams, by monitoring and perturbing neuronal activity in behaving animals. We will evaluate how these methods can be combined with mathematical modeling to test and to refine mechanistic hypothesis about elementary sensorimotor functions carried out by neural-circuit motifs. Finally, we will leverage a comparative analysis across model organisms to extract computational principles common to the biological implementations of adaptive navigational algorithms.
Application deadline: November 21, (11:59 p.m. EST)View Full Details
Neural circuits implement transfer functions that combine sensory inputs and prior experience to choose a behavioral response. Historically, the study of the most convenient animal models —from the giant axon of the squid and the lobster's stomatogastric circuits to Aplysia's synapses and C. elegans' circuits — neuroscientists revealed some of the operating principles of the nervous system, which were then found to apply broadly across phyla. The third installment of this meeting will once again bring together neuroscientists working on a broad diversity of animal models in an effort to compare circuits across phyla as a means to crack their function.
Application deadline: December 1, 2019 (11:59 p.m. ET)View Full Details
Neuropeptides comprise the largest and most diverse class of neuromodulators and regulate a diverse array of critical processes. While their importance is well-established, fundamental questions about synthesis, processing, release, transmittal, reception, and signal transduction remain unanswered. Recent tool developments and advances in experimental and genetic techniques have the potential to transform our understanding of neuropeptide function from subcellular synthesis to behavioral output. Now is an ideal time to begin redefining our understanding of how neuropeptides layer with circuitry and metabolism to govern physiological functions and behavior.
This meeting will bring together researchers studying the influence of neuropeptide signaling on physiology and behavior at both the cellular and circuit level in a range of organisms and across disciplines, including experimental and computational tool developers. Through presentations and discussions, we look forward to 1) generating new questions and hypotheses about how neuropeptides regulate behavior and how they themselves are regulated, 2) identifying questions that emerging tools could be used to address, and 3) defining new tools and strategies for probing neuropeptide function.
Application Deadline: December 19, 2019 (11:59 p.m. EST)View Full Details
The brain is constantly monitoring how one is feeling and functioning - information which is essential to evaluate if an organism is ill, hungry, or short of breath. At the least, such feedback from within enables computation and action to be prioritized for optimum output; at the extreme, it ensures survival. However, little is known about how the brain monitors and reacts to the constantly changing internal physiology. While there has been rapid progress in understanding exteroception, less is known on how we sense and process information from within the organism, such as hunger, respiration, circulation, and excretion. This conference will offer a multidisciplinary approach to discuss recent advances in interoception, by defining the signals that monitor internal states to identifying critical neuronal circuits that drive behavior.
Application Deadline: January 2, 2020 (11:59 p.m. EST)View Full Details
With the goal of improving gender diversity of life science faculty, the Leading Edge Symposium provides outstanding women and non-binary postdocs in biomedical research a platform to share their work and connect with one another, both professionally and personally. Attendees will give short research talks, participate in lively discussions and network with both junior and senior investigators. A panel of carefully selected world leaders in biomedical research will provide mentorship and career development training, and representatives from institutions interested in recruiting and supporting a diverse faculty will be invited. Successful postdoctoral applicants will have their travel expenses, meals and accommodations fully covered.
See leadingedgesymposium.org for more details and Frequently Asked Questions about this exciting conference!
We welcome both postdoctoral researchers and institutional representatives to apply.
Application deadline: January 6, 2020 (11:59 p.m. ET)View Full Details
For many years, our understanding of early mammalian development has been limited by the inability to visualize development as it happens. Technical limitations, physical inaccessibility, and complex computational problems have all hindered our ability to answer long-standing questions in the field of mouse development. Recent advances in cutting-edge light microscopy and computational tools have catapulted the field forward and presented us with new avenues and opportunities to address outstanding questions.
The third iteration of this workshop, which alternates between Janelia and EMBL Heidelberg, brings together members of the mouse developmental community with experts in the latest imaging technologies, computational image analysis and more broadly quantitative biology fields, with the goal of raising awareness about available tools and techniques, unresolved questions or challenges, while fostering discussions on how best to utilize these tools and what tools are still needed. The intimate nature of Janelia meetings fosters an interactive and collaborative environment, and we look forward to open conversations on advancing this small (but growing) field, how best to analyze and share large datasets and how to utilize the massive amount of information new imaging systems will provide.
Application Deadline: January 16, 2020 (11:59 p.m. EST)View Full Details