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Main Menu - Block
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Fly Facility
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
The animal’s body is made of diverse cell types that are neatly organized to form functional organs. Using advanced imaging and genomic tools, we devise new strategies to deconstruct mechanisms underlying spatial and temporal control of cell fates during animal development
A fertilized egg - a single cell - carrying one copy of mom's and one copy of dad's DNA is able to divide and differentiate to trillions of cells and hundreds of cell types in our body, enabling each of us to thrive in the society.
As a long-standing research direction, our lab quantitatively analyzes gene regulatory mechanisms at the single-cell, single-molecule level to discover how stereotypical cell fate choices during normal development as well as altered states in diseases emerge from seemly stochastic molecular events in the cell. To achieve this goal, we devise multidisciplinary strategies to decipher functional links between genome organization, gene regulation and molecular dynamics in culture as well as in vivo.
Currently, we have opening positions for a motivated graduate student with STEM background as well as a postdoctoral researcher with a background in imaging or genomics. If you are interested, please feel free to contact me at liuz11 at janelia.hhmi.org
"Function follows form
at present while form
follows function during
evolution."
- my take