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Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2016
Rodriguez JA, Gonen T.
2016. High-resolution macromolecular structure determination by MicroED, a cryo-EM method.. Methods in Enzymology.
Hattne J, Shi D, M de la Cruz J, Reyes FE, Gonen T.
2016. Modeling truncated pixel values of faint reflections in MicroED images.. Journal of Applied Crystallography. 49(3)
2015
Gonen S, DiMaio F, Gonen T, Baker D.
2015. Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces.. Science. 348(6241):1365-8.
Hattne J, Reyes FE, Nannenga BL, Shi D, M de la Cruz J, Leslie AGW, Gonen T.
2015. MicroED data collection and processing.. Acta Crystallographica Section A: Foundations & Advances. 71(Pt 4):353-60.
Bale JB, Park RU, Liu Y, Gonen S, Gonen T, Cascio D, King NP, Yeates TO, Baker D.
2015. Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.. Protein Science. 24(10):1695-701.
Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M et al..
2015. Structure of the toxic core of α-synuclein from invisible crystals.. Nature. 525(7570):486-90.
2014
King NP, Bale JB, Sheffler W, McNamara DE, Gonen S, Gonen T, Yeates TO, Baker D.
2014. Accurate design of co-assembling multi-component protein nanomaterials.. Nature. 510(7503):103-8.
Anderson TM, Clay MC, Cioffi AG, Diaz KA, Hisao GS, Tuttle MD, Nieuwkoop AJ, Comellas G, Maryum N, Wang S et al..
2014. Amphotericin forms an extramembranous and fungicidal sterol sponge.. Nature Chemical Biology. 10(5):400-6.
Gonen T, Waksman G.
2014. Editorial overview: Membranes: recent methods in the study of membrane protein structure.. Current Opinion in Structural Biology. 27:iv-v.
Huang P-S, Oberdorfer G, Xu C, Pei XY, Nannenga BL, Rogers JM, DiMaio F, Gonen T, Luisi B, Baker D.
2014. High thermodynamic stability of parametrically designed helical bundles.. Science. 346(6208):481-5.
Nannenga BL, Shi D, Leslie AGW, Gonen T.
2014. High-resolution structure determination by continuous-rotation data collection in MicroED.. Nature Methods. 11(9):927-30.
Nannenga BL, Gonen T.
2014. Protein structure determination by MicroED.. Current Opinion in Structural Biology. 27C:24-31.
Wisedchaisri G, Park M-S, Iadanza MG, Zheng H, Gonen T.
2014. Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.. Nature Communication. 5:4521.
Nannenga BL, Shi D, Hattne J, Reyes FE, Gonen T.
2014. Structure of catalase determined by MicroED.. eLife. 3:e03600.
Iadanza MG, Gonen T.
2014. A suite of software for processing MicroED data of extremely small protein crystals.. Journal of Applied Crystallography. 47(Pt 3):1140-45.
Russell AB, Wexler AG, Harding BN, Whitney JC, Bohn AJ, Goo YAh, Tran BQ, Barry NA, Zheng H, S Peterson B et al..
2014. A type VI secretion-related pathway in bacteroidetes mediates interbacterial antagonism.. Cell Host Microbe. 16(2):227-36.
2013
Reichow SL, Clemens DM, J Freites A, Németh-Cahalan KL, Heyden M, Tobias DJ, Hall JE, Gonen T.
2013. Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.. Nature Structural & Molecular Biology. 20(9):1085-92.
Zheng H, Wisedchaisri G, Gonen T.
2013. Crystal structure of a nitrate/nitrite exchanger.. Nature. 497(7451):647-51.
Silverman JM, Agnello DM, Zheng H, Andrews BT, Li M, Catalano CE, Gonen T, Mougous JD.
2013. Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates.. Molecular Cell. 51(5):584-93.
Filbin ME, Vollmar BS, Shi D, Gonen T, Kieft JS.
2013. HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation.. Nature Structural & Molecular Biology. 20(2):150-8.
F Smith D, Reichow SL, Esseltine JL, Shi D, Langeberg LK, Scott JD, Gonen T.
2013. Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.. eLife. 2:e01319.
Gold MG, Gonen T, Scott JD.
2013. Local cAMP signaling in disease at a glance.. Journal of Cell Science. 126(Pt 20):4537-43.
Nannenga BL, Iadanza MG, Vollmar BS, Gonen T.
2013. Overview of electron crystallography of membrane proteins: crystallization and screening strategies using negative stain electron microscopy.. Current Protocols in Protein Science . Chapter 17:Unit17.15.
Shi D, Nannenga BL, Iadanza MG, Gonen T.
2013. Three-dimensional electron crystallography of protein microcrystals.. eLife. 2:01345.