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We want to establish the mechanisms by which microcircuits in the hippocampus and cortex encode, maintain and dynamically update information, and relate these to phenomena expressed at the level of behavior.
The medial temporal lobe is considered the fundamental substrate of episodic memory, mediating the acquisition of events unfolding with particular spatial and temporal relationships (what, where, and when). The initial retrieval of past events can be triggered by specific sensory cues, but the retrieval dynamics recapitulating an entire episode evolve independently of external cues and are supported by activity patterns intrinsically generated in cortical circuits. Our aim is to understand the neuronal mechanisms underlying these dynamics.
Short-term synaptic plasticity: Mean-field models
Continuous attractors: Storage of correlated manifolds
Recognition memory: One-shot learning
Memory retrieval: Scaling laws