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Animals can transition to and maintain vastly different physiological states, such as during infections. We use a combination of molecular, cellular, and systems level tools to study how the nervous system contributes to these processes.
While our body has the remarkable capacity to maintain our physiology within a narrow range, it can also drastically change our physiology in response to both external and internal stimuli. These physiological state changes can be transient, for minutes or hours, or can last for much longer, on the order of days and weeks. Our lab is interested in understanding the role of the nervous system in coordinating the required changes in behavior, autonomic function, and metabolism for these shifts in physiological state.
We are particularly interested in studying the mechanisms of dramatic, adaptive states such as our response to infection, termed sickness. To interrogate this, we use a combination of molecular profiling, cellular imaging, functional manipulations, and organism-level phenotyping in both mice and zebrafish.
We are always excited to hear from people who share our research interests. We have opportunities in the lab for senior scientists, postdoctoral researchers, research technicians, and summer undergraduate students.