Gene regulation: the HSP70 gene jumps when shocked.

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Current Biology. 2014 May 19;24(10):R396-8. doi: 10.1016/j.cub.2014.03.070

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Gene regulation: the HSP70 gene jumps when shocked. Singer Lab

Vera M, Singer RH

Note: Research in this publication was not performed at Janelia.

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Abstract

Limited chromosome mobility has been observed in mammalian interphase nuclei. Live imaging shows unidirectional and actin-dependent movement of HSP70 loci towards speckles upon heat shock, resulting in enhanced transcription. This adds further impetus to understanding compartmentalization of function in the nucleus.

PMID: 24845669 [PubMed - indexed for MEDLINE]

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Gene regulation: the HSP70 gene jumps when shocked.

Note: Research in this publication was not performed at Janelia.

Abstract

PMID: 24845669 [PubMed - indexed for MEDLINE]

Janelia Authors