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Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail.

Cortés-Medina LV, Pasantes-Morales H, Aguilera-Castrejon A, Picones A, Lara-Figueroa CO, Luis E, Montesinos JJose, Cortés-Morales VA, Ruiz MPDe la Ro, Hernández-Estévez E et al.. 2019. Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail.. Stem Cells Int. 2019:7627148.

Context-dependent functional compensation between Ythdf mA reader proteins.

Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera-Castrejon A, Schneir D, Bayerl J, Mizrahi O, Peles S, Tawil S et al.. 2020. Context-dependent functional compensation between Ythdf mA reader proteins.. Genes Dev. 34(19-20):1373-1391.

Principles of signaling pathway modulation for enhancing human naive pluripotency induction.

Bayerl J, Ayyash M, Shani T, Manor YShlomo, Gafni O, Massarwa R, Kalma Y, Aguilera-Castrejon A, Zerbib M, Amir H et al.. 2021. Principles of signaling pathway modulation for enhancing human naive pluripotency induction.. Cell Stem Cell. 28(9):1549-1565.e12.

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.

Aguilera-Castrejon A, Oldak B, Shani T, Ghanem N, Itzkovich C, Slomovich S, Tarazi S, Bayerl J, Chugaeva V, Ayyash M et al.. 2021. Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.. Nature. 593(7857):119-124.

Ex Utero Culture of Mouse Embryos from Pregastrulation to Advanced Organogenesis.

Aguilera-Castrejon A, Hanna JH. 2021. Ex Utero Culture of Mouse Embryos from Pregastrulation to Advanced Organogenesis.. J Vis Exp. (176)

SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity

Sheban D, Shani T, Maor R, Aguilera-Castrejon A, Mor N, Oldak B, Shmueli MD, Eisenberg-Lerner A, Bayerl J, Hebert J et al.. 2022. SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity. Molecular Cell. 82:106-122.e9.

Recent insights into mammalian natural and synthetic ex utero embryogenesis

Oldak B, Aguilera-Castrejon A, Hanna JH. 2022. Recent insights into mammalian natural and synthetic ex utero embryogenesis. Current Opinion in Genetics & Development. 77:101988.

Human primed and naïve PSCs are both able to differentiate into trophoblast stem cells.

Viukov S, Shani T, Bayerl J, Aguilera-Castrejon A, Oldak B, Sheban D, Tarazi S, Stelzer Y, Hanna JH, Novershtern N. 2022. Human primed and naïve PSCs are both able to differentiate into trophoblast stem cells.. Stem Cell Reports. 17(11):2484-2500.

Embryo model completes gastrulation to neurulation and organogenesis.

Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen D-Y, Aguilera-Castrejon A, Hanna JH et al.. 2022. Embryo model completes gastrulation to neurulation and organogenesis.. Nature. 610(7930):143-153.

Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs

Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, Wildschutz E, Haddad M, Oldak B, Gomez-Cesar E et al.. 2022. Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell. 185:3290-3306.e25.