Main Menu (Mobile)- Block

Main Menu - Block

Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues.

Our Research / Publications
janelia7_blocks-janelia7_biblio_header | block
Nature Communications. 2018 Mar 28;9(1):1260. doi: 10.1038/s41467-018-03520-5
View Article on
Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues. Zlatic LabTruman Lab
Humberg T, Bruegger P, Afonso B, Zlatic M, Truman JW, Gershow M, Samuel A, Sprecher SG
janelia7_blocks-janelia7_biblio_abstract | block

Abstract

To integrate changing environmental cues with high spatial and temporal resolution is critical for animals to orient themselves. Drosophila larvae show an effective motor program to navigate away from light sources. How the larval visual circuit processes light stimuli to control navigational decision remains unknown. The larval visual system is composed of two sensory input channels, Rhodopsin5 (Rh5) and Rhodopsin6 (Rh6) expressing photoreceptors (PRs). We here characterize how spatial and temporal information are used to control navigation. Rh6-PRs are required to perceive temporal changes of light intensity during head casts, while Rh5-PRs are required to control behaviors that allow navigation in response to spatial cues. We characterize how distinct behaviors are modulated and identify parallel acting and converging features of the visual circuit. Functional features of the larval visual circuit highlight the principle of how early in a sensory circuit distinct behaviors may be computed by partly overlapping sensory pathways.

PMID: 29593252 [PubMed - indexed for MEDLINE]

node:body | entity_field
janelia7_blocks-janelia7_biblio_authors | block

Janelia Authors

Marta Zlatic
Jim Truman
janelia7_blocks-janelia7_biblio_tools | block