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Nature. 2006 Nov 16;444(7117):288-94. doi: 10.1038/nature05401
The receptors and cells for mammalian taste. Zuker Lab
Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS
Note: Research in this publication was not performed at Janelia.
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Abstract
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired to elicit stereotypic responses.
PMID: 17108952 [PubMed - indexed for MEDLINE]
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