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Cold Spring Harbor Protocols. 2017 Apr 03;2017(4):pdb.top087304. doi: 10.1101/pdb.top087304
Whole-cell recording in the awake brain. Lee (Albert) Lab
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Abstract
Intracellular recording is an essential technique for investigating cellular mechanisms underlying complex brain functions. Despite the high sensitivity of the technique to mechanical disturbances, intracellular recording has been applied to awake, behaving, and even freely moving, animals. Here we summarize recent advances in these methods and their application to the measurement and manipulation of membrane potential dynamics for understanding neuronal computations in behaving animals.
PMID: 28373516 [PubMed - indexed for MEDLINE]
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Janelia Authors
Albert Lee
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