Main Menu (Mobile)- Block
- Overview
-
Support Teams
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
- Open Science
- You + Janelia
- About Us
Labs:
Project Teams:
Main Menu - Block
Labs:
Project Teams:
- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Invertebrate Shared Resource
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
- Project Pipeline Support
- Project Technical Resources
- Quantitative Genomics
- Scientific Computing Software
- Scientific Computing Systems
- Viral Tools
- Vivarium
2014
Iadanza MG, Gonen T.
2014. A suite of software for processing MicroED data of extremely small protein crystals.. Journal of Applied Crystallography. 47(Pt 3):1140-45.
Russell AB, Wexler AG, Harding BN, Whitney JC, Bohn AJ, Goo YAh, Tran BQ, Barry NA, Zheng H, S Peterson B et al..
2014. A type VI secretion-related pathway in bacteroidetes mediates interbacterial antagonism.. Cell Host Microbe. 16(2):227-36.
2015
Gonen S, DiMaio F, Gonen T, Baker D.
2015. Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces.. Science. 348(6241):1365-8.
Hattne J, Reyes FE, Nannenga BL, Shi D, M de la Cruz J, Leslie AGW, Gonen T.
2015. MicroED data collection and processing.. Acta Crystallographica Section A: Foundations & Advances. 71(Pt 4):353-60.
Bale JB, Park RU, Liu Y, Gonen S, Gonen T, Cascio D, King NP, Yeates TO, Baker D.
2015. Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.. Protein Science. 24(10):1695-701.
Rodriguez JA, Ivanova MI, Sawaya MR, Cascio D, Reyes FE, Shi D, Sangwan S, Guenther EL, Johnson LM, Zhang M et al..
2015. Structure of the toxic core of α-synuclein from invisible crystals.. Nature. 525(7570):486-90.
2016
Sawaya MR, Rodriguez J, Cascio D, Collazo MJ, Shi D, Reyes FE, Hattne J, Gonen T, Eisenberg DS.
2016. Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.. Proceedings of the National Academy of Sciences of the United States of America. 113(40):11232-6.
Bale JB, Gonen S, Liu Y, Sheffler W, Ellis D, Thomas C, Cascio D, Yeates TO, Gonen T, King NP et al..
2016. Accurate design of megadalton-scale two-component icosahedral protein complexes.. Science (New York, N.Y.). 353(6297):389-94.
Shi D, Nannenga BL, M de la Cruz J, Liu J, Sawtelle S, Calero G, Reyes FE, Hattne J, Gonen T.
2016. The collection of MicroED data for macromolecular crystallography.. Nature Protocols. 11(5):895-904.
Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D et al..
2016. Data publication with the structural biology data grid supports live analysis.. Nature Communications. 7:10882.
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang P-S, Ravichandran R et al..
2016. Design of a hyperstable 60-subunit protein icosahedron.. Nature.
Rodriguez JA, Gonen T.
2016. High-resolution macromolecular structure determination by MicroED, a cryo-EM method.. Methods in Enzymology.
Hattne J, Shi D, M de la Cruz J, Reyes FE, Gonen T.
2016. Modeling truncated pixel values of faint reflections in MicroED images.. Journal of Applied Crystallography. 49(3)
2017
Krotee P, Rodriguez JA, Sawaya MR, Cascio D, Reyes FE, Shi D, Hattne J, Nannenga BL, Oskarsson ME, Philipp S et al..
2017. Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity.. eLife. 6
M de la Cruz J, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SKyung et al..
2017. Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.. Nature Methods. 14(4):399-402.
Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J et al..
2017. Common fibrillar spines of amyloid-β and human Islet Amyloid Polypeptide revealed by Micro Electron Diffraction and inhibitors developed using structure-based design.. The Journal of Biological Chemistry. 293(8):2888-902.
Hughes MP, Sawaya MR, Goldschmidt L, Rodriguez JA, Cascio D, Gonen T, Eisenberg DS.
2017. Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets.. bioRxiv.
de la Cruz MJason, Martynowycz M, Hattne J, Shi D, Gonen T.
2017. A method to minimize condenser lens-induced hysteresis effects in a JEOL JEM-3200FSC microscope to enable stable cryoEM low-dose operations.. bioRxiv.
Vergara S, Lukes DA, Martynowycz MW, Santiago U, Plascencia-Villa G, Weiss SC, de la Cruz MJason, Black DM, Alvarez MM, Lopez-Lozano X et al..
2017. MicroED structure of Au146(p-MBA)57 at subatomic resolution reveals a twinned FCC cluster.. Journal of Physical Chemistry Letters. 8(5523-30):arXiv:1706.07902[physics.atm-clus].
Martynowycz M, Glynn C, Miao J, de la Cruz MJason, Hattne J, Shi D, Cascio D, Rodriguez J, Gonen T.
2017. MicroED structures from micrometer thick protein crystals.. bioRxiv.
Wright ZVF, McCarthy S, Dickman R, Reyes FE, Sanchez-Martinez S, Cryar A, Kilford I, Hall A, Takle AK, Topf M et al..
2017. The role of disulfide bond replacements in analogues of the tarantula toxin ProTx-II and their effects on inhibition of the voltage-gated sodium ion channel Nav1.7.. Journal of the American Chemical Society. 139(37):13063-75.
Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS.
2017. Structure-based inhibitors of tau aggregation.. Nature Chemistry.
Rodriguez JA, Eisenberg DS, Gonen T.
2017. Taking the measure of MicroED.. Current Opinion in Structural Biology. 46:79-86.
2018
Hattne J, Shi D, Glynn C, Zee C-T, Gallagher-Jones M, Martynowycz MW, Rodriguez JA, Gonen T.
2018. Analysis of global and site-specific radiation damage in cryo-EM.. Structure (London, England : 1993). 26(5):759-66.
Guenther EL, Ge P, Trinh H, Sawaya MR, Cascio D, Boyer DR, Gonen T, Z Zhou H, Eisenberg DS.
2018. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.. Nature Structural & Molecular Biology.