Zhang, Q., Dang, W., Wang, M.C. (2025) Lysosome signal through epigenome to regulate longevity across generations. Science 389(6767):1353-1360
Zhang, H., Ding, L., Hu, A., Shi, X., Huang, P., Lu, H., Tillberg, P.W.*, Wang, M.C.*, Li, L.* (2025) TEMI: Tissue Expansion Mass spectrometry Imaging. Nat Methods 22(5):1051-1058
Hu, G., Savini, M., Cooke, M.B., Wei, X., Deng, D., Gao, S.M., Xia, A., Guan, Y., Wen, A.X., Yu, X., Wang, J., Jiang, C., Herman, C., Li, J., Wang, M.C. (2025) Chemical modulation of gut bacterial metabolism induces colanic acid and extends the lifespan of nematode and mammalian hosts. PLoS Biol 23(11):e3002749
Gao, S.M., Qi, Y., Zhang, Q., Guan, Y., Lee, Y., Ding, L., Wang, L., Mohammed, A.S., Li, H., Fu, Y., Wang, M.C. (2024) Aging atlas reveals cell-type-specific effects of pro-longevity strategies. Nat Aging 4:998-1013
Yu, Y., Gao, S.M., Guan, Y., Hu, P., Zhang, Q., Liu, J., Jing, B., Zhao, Q., Sabatini, D.M., Abu-Remaileh, M., Jung, S.Y., Wang, M.C. (2024) Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity. Elife 13:e85214
Lee, Y., Savini, M., Chen, T., Yang, J., Zhao, Q., Ding, L., Gao, S.M., Senturk, M., Sowa, J., Wang, J.D., Wang, M.C. (2023) Mitochondrial GTP metabolism regulates reproductive aging. Dev Cell 58(23):2718-2731
Savini, M., Folick, A., Lee, Y., Jin, F., Cuevas, A., Tillman, M., Duffy, J., Zhao, Q., Neve, I., Hu, P., Yu, Y., Zhang, Q., Ye, Y., Mair, W., Wang, J., Han, L., Ortlund, E.A., Wang, M.C. (2022) Lysosome lipid signaling from the periphery to neurons regulates longevity. Nat Cell Biol 24(6):906-916
Mutlu, A.S., Gao, S.M., Zhang, H. Wang, M.C. (2020) Olfactory specificity regulates lipid metabolism through neuroendocrine signaling. Nat Commun 11(1):1450
Hartsough, L.A., Pak, M., Kotlajich, M.V., Lazar, J.T., Han, B., Lin, C.J., Musteata, E., Gambill, L., Wang, M.C. *, Tabor, J.J. * (2020) Optogenetic control of gut bacterial metabolism to promote longevity. eLife 9:e5684939.
Choi, S., Lin, C.J., Kim, K.H., Wagner, M., Wang, M.C. *, Moore, D.D.* (2020) Methyl-sensing nuclear receptor Liver Receptor Homolog-1 regulates mitochondrial biogenesis and beta-oxidation in mouse hepatocytes. Hepatology 71(3):1055-1069
Ramachandran PV, Savini M, Folick AK, Hu K, Masand R, Graham BH, Wang MC "Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity.." Dev Cell..2019;48:685-696.e5..
Bing, H., Sivaramakrishnan, P., Lin, C.J., Neve, I.A.A, Sowa, J.N., He, J., Tay, L.W.R., Sizovs, A., Du, G., Wang, J., Herman, C., Wang, M.C. "Microbial genetic composition tunes host longevity." Cell.2017/June;169(7):1249-62. Pubmed PMID: 28622510
Lin, C., Wang, M.C. "Microbial Metabolites Regulate Host Lipid Metabolism through NR5A-Hedgehog signaling." Nat Cell Biol.2017/May;19(5):550-7. Pubmed PMID: 28436966
Yu Y, Mutlu AS, Liu H, Wang MC "High-throughput screens using photo-highlighting discover BMP signaling in mitochondrial lipid oxidation.." Nat Commun..2017;8:865.
Folick A, Oakley HD, Yu Y, Armstrong EH, Kumari M, Sanor L, Moore DD, Ortlund EA, Zechner R, Wang MC "Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.." Science. 2015 347 : 83-6.
Sowa JN, Mutlu AS, Xia F, Wang MC "Olfaction Modulates Reproductive Plasticity through Neuroendocrine Signaling in Caenorhabditis elegans.." Curr Biol. 2015 August 12; 25 : 2284-9. Pubmed PMID: 26279229
Folick A, Oakley HD, Yu Y, Armstrong EH, Kumari M, Sanor L, Moore DD, Ortlund EA, Zechner R, Wang MC "Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans." Science. 2015 January 2; 347 (6217): 83-6. Pubmed PMID: 25554789
Fu D, Yu Y, Folick A, Currie E, Farese RV Jr, Tsai TH, Xie XS, Wang MC "In vivo metabolic fingerprinting of neutral lipids with hyperspectral stimulated Raman scattering microscopy." J Am Chem Soc. 2014 June 18; 136 (24): 8820-8. Pubmed PMID: 24869754
Wang MC, Oakley HD, Carr CE, Sowa JN, Ruvkun G "Gene pathways that delay Caenorhabditis elegans reproductive senescence.." PLoS Genet. 2014 December 4; 10 : e1004752. Pubmed PMID: 25474471
Wei L, Yu Y, Shen Y, Wang MC, Min W. "Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy." Proc Natl Acad Sci U S A. 2013 July 9; 110 (28): 11226-31. Pubmed PMID: 23798434
Wang MC, Min W, Freudiger CW, Ruvkun G, Xie XS. "RNAi screening for fat regulatory genes with SRS microscopy." Nat Methods. 2011 February ; 8 (2): 135-8. Pubmed PMID: 21240281