Biblio

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Author Title Type [ Year(Desc)]
Filters: Author is Grimm, Jonathan B  [Clear All Filters]
2003
Grimm JB, Stables JP, Brown ML.  2003.  Design, synthesis, and development of novel caprolactam anticonvulsants.. Bioorganic & Medicinal Chemistry. 11(18):4133-41.
2004
Grimm JB, Lee D.  2004.  Efficient synthesis of alkynylsilyl ethers and silaketals via base-induced alkynylsilane alcoholysis.. The Journal of Organic Chemistry. 69(25):8967-70.
2007
Kim YJin, Grimm JB, Lee D.  2007.  Absence of the Thorpe-Ingold Eet by gem-diphenyl groups in ring-closing enyne metathesis.. Tetrahedron Letters. 48(45):7961-4.
Grimm JB, Katcher MH, Witter DJ, Northrup AB.  2007.  A new strategy for the synthesis of benzylic sulfonamides: palladium-catalyzed arylation and sulfonamide metathesis.. The Journal of Organic Chemistry. 72(21):8135-8.
2008
Wilson KJ, Witter DJ, Grimm JB, Siliphaivanh P, Otte KM, Kral AM, Fleming JC, Harsch A, Hamill JE, Cruz JC et al..  2008.  Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).. Bioorganic & Medicinal Chemistry Letters. 18(6):1859-63.
2009
Grimm JB, Wilson KJ, Witter DJ.  2009.  A divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.. The Journal of Organic Chemistry. 74(16):6390-3.
Heidebrecht RW, Chenard M, Close J, Dahlberg WK, Fleming J, Grimm JB, Hamill JE, Harsch A, Haines BB, Hughes B et al..  2009.  Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).. Bioorganic & Medicinal Chemistry Letters. 19(7):2053-8.
2011
Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.  2011.  Facile and general synthesis of photoactivatable xanthene dyes.. Angewandte Chemie. 50:11206-9.
Grimm JB, Lavis LD.  2011.  Synthesis of rhodamines from fluoresceins using Pd-catalyzed C-N cross-coupling.. Organic Letters. 13(24):6354-7.
2013
Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.  2013.  Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.. ACS Chemical Biology. 8(6):1303-10.
Grimm JB, Heckman LM, Lavis LD.  2013.  The chemistry of small-molecule fluorogenic probes.. Progress in Molecular Biology and Translational Science. 113:1-34.
Kopek BG, Shtengel G, Grimm JB, Clayton DA, Hess HF.  2013.  Correlative photoactivated localization and scanning electron microscopy.. PLoS One. 8(10):e77209.
2014
Liu Z, Legant WR, Chen B-C, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.  2014.  3D imaging of Sox2 enhancer clusters in embryonic stem cells.. eLife. 3
Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.  2014.  Single-molecule tracking of the transcription cycle by sub-second RNA detection.. eLife. 3:e01775.
2015
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH et al..  2015.  A general method to improve fluorophores for live-cell and single-molecule microscopy.. Nature Methods. 12(3):244-50.
Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.  2015.  Synthesis of a far-red photoactivatable silicon-containing rhodamine for super-resolution microscopy.. Angewandte Chemie (International ed. in English). 55(5):1723-7.
2016
Lavis LD, Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z et al..  2016.  Bright photoactivatable fluorophores for single-molecule imaging.. Nature Methods. 13(12):985-8.
Heckman LM, Grimm JB, Schreiter ER, Kim C, Verdecia MA, Shields BC, Lavis LD.  2016.  Design and synthesis of a calcium-sensitive photocage.. Angewandte Chemie (International ed. in English).
Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.  2016.  Glutamate-induced RNA localization and translation in neurons.. Proceedings of the National Academy of Sciences of the United States of America.
Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.  2016.  High-density three-dimensional localization microscopy across large volumes.. Nature Methods.
Zhen CYu, Tatavosian R, Huynh TNgoc, Duc HNguyen, Das R, Kokotovic M, Grimm JB, Lavis LD, Lee J, Mejia FJ et al..  2016.  Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.. eLife. 5
Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG et al..  2016.  Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.. Genes and Development. 30:2106-18.
Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.  2016.  Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.. eLife. 5
Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL.  2016.  Real-time quantification of single RNA translation dynamics in living cells.. Science. 352(6292):1425-9.
Cho W-K, Jayanth N, English BP, Inoue T, J Andrews O, Conway W, Grimm JB, Spille J-H, Lavis LD, Lionnet T et al..  2016.  RNA Polymerase II cluster dynamics predict mRNA output in living cells.. eLife. 5