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- Overview
- Anatomy and Histology
- Cryo-Electron Microscopy
- Electron Microscopy
- Flow Cytometry
- Fly Facility
- Gene Targeting and Transgenics
- Immortalized Cell Line Culture
- Integrative Imaging
- Janelia Experimental Technology
- Mass Spectrometry
- Media Prep
- Molecular Genomics
- Primary & iPS Cell Culture
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- Quantitative Genomics
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Export 25 results:
Author Title Type [ Year
] Filters: Author is Akerboom, Jasper [Clear All Filters]
2021
Kim H-S, Kim J-E, Hwangbo A, Akerboom J, Looger LL, Duncan R, Son H, Czymmek KJ, Kang S.
2021. Evaluation of multi-color genetically encoded Ca indicators in filamentous fungi.. Fungal Genetics and Biology. :103540.
2013
Akerboom J, Calderón NCarreras, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ et al..
2013. Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.. Frontiers in Molecular Neuroscience. 6:2.
Marvin JS, Borghuis BG, Tian L, Cichon J, Harnett MT, Akerboom J, Gordus A, Renninger SL, Chen T-W, Bargmann CI et al..
2013. An optimized fluorescent probe for visualizing glutamate neurotransmission.. Nature Methods. 10:162-70.
2012
Tian L, Akerboom J, Schreiter ER, Looger LL.
2012. Neural activity imaging with genetically encoded calcium indicators.. Progress in Brain Research. 196:79-94.
Akerboom J, Chen T-W, Wardill TJ, Marvin JS, Mutlu S, Caldero NCarreras, Esposti F, Borghuis BG, Sun XRichard, Gordus A et al..
2012. Optimization of a GCaMP calcium indicator for neural activity imaging.. The Journal of Neuroscience. 32:13819-40.
Husson SJ, Costa WSteuer, Wabnig S, Stirman JN, Watson JD, W Spencer C, Akerboom J, Looger LL, Treinin M, Miller DM et al..
2012. Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors.. Current Biology. 22(9):743-52.
2010
Tang J, Akerboom J, Vaziri A, Looger LL, Shank CV.
2010. Near-isotropic 3D optical nanoscopy with photon-limited chromophores.. Proceedings of the National Academy of Sciences of the United States of America. 107(22):10068-73.
2009
Kuipers RKP, Joosten H-J, Verwiel E, Paans S, Akerboom J, van der Oost J, Leferink NGH, van Berkel WJH, Vriend G, Schaap PJ.
2009. Correlated mutation analyses on super-family alignments reveal functionally important residues.. Proteins. 76(3):608-16.
Akerboom J, Rivera JDVélez, Guilbe MMRodrígu, Malavé ECAlfaro, Hernandez HH, Tian L, S Hires A, Marvin JS, Looger LL, Schreiter ER.
2009. Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design.. The Journal of Biological Chemistry. 284:6455-64.
Tian L, S Hires A, Mao T, Huber D, M Chiappe E, Chalasani SH, Petreanu L, Akerboom J, McKinney SA, Schreiter ER et al..
2009. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators.. Nature Methods. 6(12):875-81.
2008
Guilbe MMRodrígu, Malavé ECAlfaro, Akerboom J, Marvin JS, Looger LL, Schreiter ER.
2008. Crystallization and preliminary x-ray characterization of the genetically encoded fluorescent calcium indicator protein GCaMP2.. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64:629-31.
Brouns SJJ, Barends TRM, Worm P, Akerboom J, Turnbull AP, Salmon L, van der Oost J.
2008. Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.. Journal of Molecular Biology. 379:357-71.
2007
van Loo SWolterink-, van Eerde A, Siemerink MAJ, Akerboom J, Dijkstra BW, van der Oost J.
2007. Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases.. The Biochemical Journal. 403(3):421-30.
Brouns SJJ, Turnbull AP, Willemen HLDM, Akerboom J, van der Oost J.
2007. Crystal structure and biochemical properties of the D-arabinose dehydrogenase from Sulfolobus solfataricus.. Journal of Molecular Biology. 371(5):1249-60.
Akerboom J.
2007. Functional analysis of thermostable proteins involved in carbohydrate metabolism.. :174.
Kanai T, Akerboom J, Takedomi S, van de Werken HJG, Blombach F, van der Oost J, Murakami T, Atomi H, Imanaka T.
2007. A global transcriptional regulator in Thermococcus kodakaraensis controls the expression levels of both glycolytic and gluconeogenic enzyme-encoding genes.. The Journal of Biological Chemistry. 282:33659-70.
Wu H, Sun L, Brouns SJJ, Fu S, Akerboom J, Li X, van der Oost J.
2007. Purification, crystallization and preliminary crystallographic analysis of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus.. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63:239-41.
2006
Berrisford JM, Hounslow AM, Akerboom J, Hagen WR, Brouns SJJ, van der Oost J, Murray IA, G Blackburn M, Waltho JP, Rice DW et al..
2006. Evidence supporting a cis-enediol-based mechanism for Pyrococcus furiosus phosphoglucose isomerase.. Journal of Molecular Biology. 358(5):1353-66.
van de Werken HJG, Verhees CH, Akerboom J, de Vos WM, van der Oost J.
2006. Identification of a glycolytic regulon in the archaea Pyrococcus and Thermococcus.. FEMS Microbiology Letters. 260(1):69-76.
Thaw P, Sedelnikova SE, Muranova T, Wiese S, Ayora S, Alonso JC, Brinkman AB, Akerboom J, van der Oost J, Rafferty JB.
2006. Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family.. Nucleic Acids Research. 34(5):1439-49.
2005
Brouns SJJ, Wu H, Akerboom J, Turnbull AP, de Vos WM, van der Oost J.
2005. Engineering a selectable marker for hyperthermophiles.. The Journal of Biological Chemistry. 280(12):11422-31.
2004
Berrisford JM, Akerboom J, Brouns S, Sedelnikova SE, Turnbull AP, van der Oost J, Salmon L, Hardré R, Murray IA, G Blackburn M et al..
2004. The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.. Journal of Molecular Biology. 343(3):649-57.
2003
Berrisford JM, Akerboom J, Turnbull AP, de Geus D, Sedelnikova SE, Staton I, McLeod CW, Verhees CH, van der Oost J, Rice DW et al..
2003. Crystal structure of Pyrococcus furiosus phosphoglucose isomerase. Implications for substrate binding and catalysis.. The Journal of Biological Chemistry. 278(35):33290-7.
Akerboom J, Turnbull AP, Hargreaves D, Fisher M, de Geus D, Sedelnikova SE, Berrisford JM, Baker PJ, Verhees CH, van der Oost J et al..
2003. Purification, crystallization and preliminary crystallographic analysis of phosphoglucose isomerase from the hyperthermophilic archaeon Pyrococcus furiosus.. Acta Crystallographica. Section D, Biological Crystallography. 59:1822-3.
2002
Verhees CH, Akerboom J, Schiltz E, de Vos WM, van der Oost J.
2002. Molecular and biochemical characterization of a distinct type of fructose-1,6-bisphosphatase from Pyrococcus furiosus.. Journal of Bacteriology. 184(12):3401-5.