| Page 5 | Janelia Research Campus

Combining spatial transcriptomics and ECM imaging in 3D for mapping cellular interactions in the tumor microenvironment.

Pentimalli TMassimo, Schallenberg S, León-Periñán D, Legnini I, Theurillat I, Thomas G, Boltengagen A, Fritzsche S, Nimo J, Ruff L et al.. 2025. Combining spatial transcriptomics and ECM imaging in 3D for mapping cellular interactions in the tumor microenvironment.. Cell Syst. :101261.

A Bayesian Model to Count the Number of Two-State Emitters in a Diffraction Limited Spot.

Hillsley A, Stein J, Tillberg PW, Stern DL, Funke J. 2025. A Bayesian Model to Count the Number of Two-State Emitters in a Diffraction Limited Spot.. Nano Lett.

Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals.

Mi X, Chen ABo-Yuan, Duarte D, Carey E, Taylor CR, Braaker PN, Bright M, Almeida RG, Lim J-X, Ruetten VMS et al.. 2025. Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals.. Cell.

Far-red fluorescent genetically encoded calcium ion indicators.

Dalangin R, Jia BZ, Qi Y, Aggarwal A, Sakoi K, Drobizhev M, Molina RS, Patel R, Abdelfattah AS, Zheng J et al.. 2025. Far-red fluorescent genetically encoded calcium ion indicators.. Nat Commun. 16(1):3318.

Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety.

Zhu Z, Gong R, Rodriguez V, Quach KT, Chen X, Sternson SM. 2025. Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety.. Science. 387(6741):eadt0773.

DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning.

Mohar B, Michel G, Wang Y-Z, Hernandez V, Grimm JB, Park J-Y, Patel R, Clarke M, Brown TA, Bergmann C et al.. 2025. DELTA: a method for brain-wide measurement of synaptic protein turnover reveals localized plasticity during learning.. Nat Neurosci.

EPSILON: a method for pulse-chase labeling to probe synaptic AMPAR exocytosis during memory formation.

Kim D, Park P, Li X, J Wong-Campos D, Tian H, Moult EM, Grimm JB, Lavis LD, Cohen AE. 2025. EPSILON: a method for pulse-chase labeling to probe synaptic AMPAR exocytosis during memory formation.. Nat Neurosci.

Whole-brain, all-optical interrogation of neuronal dynamics underlying gut interoception in zebrafish

Chen W, James B, Ruetten VMS, Banala S, Wei Z, Fleishman G, Rubinov M, Fishman MC, Engert F, Lavis LD et al.. 2025. Whole-brain, all-optical interrogation of neuronal dynamics underlying gut interoception in zebrafish. bioRxiv.

Fourier-Based 3D Multistage Transformer for Aberration Correction in Multicellular Specimens

Alshaabi T, Milkie D, Liu G, Shirazinejad C, Hong J, Achour K, Görlitz F, Milunovic-Jevtic A, Simmons C, Abuzahriyeh I et al.. 2025. Fourier-Based 3D Multistage Transformer for Aberration Correction in Multicellular Specimens. Research Square.

Glutamate indicators with increased sensitivity and tailored deactivation rates

Aggarwal A, Negrean A, Chen Y, Iyer R, Reep D, Liu A, Palutla A, Xie ME, MacLennan BJ, Hagihara KM et al.. 2025. Glutamate indicators with increased sensitivity and tailored deactivation rates. bioRxiv.