Biblio

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2026
Fu T-M, Liu G, Milkie DE, Ruan X, Görlitz F, Shi Y, Ferro V, Divekar NS, Wang W, York HM et al..  2026.  A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms. Nat Methods.
Abidi AA, Cattoglio C, Tang NN, Fan VB, Dailey GM, Hay AD, Kunamaneni P, Milkie DE, Darzacq X, Betzig E et al..  2026.  Unstructured transcription factor interactions enable emergent specificity.. Science. :eaeb6487.
2025
Alshaabi T, Milkie DE, Liu G, Shirazinejad C, Hong JL, Achour K, Görlitz F, Milunovic-Jevtic A, Simmons C, Abuzahriyeh IS et al..  2025.  Fourier-based three-dimensional multistage transformer for aberration correction in multicellular specimens.. Nat Methods.
2024
Betzig E.  2024.  A Cell Observatory to reveal the subcellular foundations of life.. Nat Methods.
Wang W, Ruan X, Liu G, Milkie DE, Li W, Betzig E, Upadhyayula S, Gao R.  2024.  Nanoscale volumetric fluorescence imaging via photochemical sectioning. bioRxiv.
2023
Emmerich K, White DT, Kambhampati SP, Casado GL, Fu T-M, Chunawala Z, Sahoo A, Nimmagadda S, Krishnan N, Saxena MT et al..  2023.  Nanoparticle-based targeting of microglia improves the neural regeneration enhancing effects of immunosuppression in the zebrafish retina.. Communications Biology. 6(1):534.
Wong KKin Lam, Li T, Fu T-M, Liu G, Lyu C, Kohani S, Xie Q, Luginbuhl DJ, Upadhyayula S, Betzig E et al..  2023.  Origin of wiring specificity in an olfactory map revealed by neuron type-specific, time-lapse imaging of dendrite targeting.. eLife. 12
Abdelfattah AS, Zheng J, Singh A, Huang Y-C, Reep D, Tsegaye G, Tsang A, Arthur BJ, Rehorova M, Olson CVL et al..  2023.  Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator. Neuron. 111(10):1547-1563.
2022
Mondal C, Gacha-Garay MJ, Larkin KA, Adikes RC, Di Martino JS, Chien C-C, Fraser M, Eni-Aganga I, Agullo-Pascual E, Cialowicz K et al..  2022.  A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling.. Cell Reports. 40(12):111358.
Moore RP, Fogerson SM, U Tulu S, Yu JW, Cox AH, Sican MA, Li D, Legant WR, Weigel AV, Crawford JM et al..  2022.  Super-resolution microscopy reveals actomyosin dynamics in medioapical arrays.. Molecular Biology of the Cell. :mbcE21110537.
Moore RP, Fogerson SM, U Tulu S, Yu JW, Cox AH, Sican MA, Li D, Legant WR, Weigel AV, Crawford JM et al..  2022.  Superresolution microscopy reveals actomyosin dynamics in medioapical arrays.. Molecular Biology of the Cell. 33(11):ar94.
2021
Li T, Fu T-M, Wong KKin Lam, Li H, Xie Q, Luginbuhl DJ, Wagner MJ, Betzig E, Luo L.  2021.  Cellular bases of olfactory circuit assembly revealed by systematic time-lapse imaging.. Cell. 184(20):5107.
Willy NM, Ferguson JP, Akatay A, Huber S, Djakbarova U, Silahli S, Cakez C, Hasan F, Chang HC, Travesset A et al..  2021.  De novo endocytic clathrin coats develop curvature at early stages of their formation.. Development Cell. 56(22):3146-3159.e5.
2020
Xie L, Dong P, Chen X, Hsieh T-HS, Banala S, De Marzio M, English BP, Qi Y, Jung SKyoung, Kieffer-Kwon K-R et al..  2020.  3D ATAC-PALM: super-resolution imaging of the accessible genome.. Nature Methods. 17(4):430-6.
Bai X, Melesse M, Turpin CGSorensen, Sloan D, Chen C-Y, Wang W-C, Lee P-Y, Simmons JR, Nebenfuehr B, Mitchell D et al..  2020.  Aurora B functions at the apical surface after specialized cytokinesis during morphogenesis in C. elegans.. Development. 147(1):1-16.
Hoffman DP, Shtengel G, C Xu S, Campbell KR, Freeman M, Wang L, Milkie DE, H Pasolli A, Iyer N, Bogovic JA et al..  2020.  Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells.. Science. 367(6475)
Hoffman DP, Betzig E.  2020.  Tiled reconstruction improves structured illumination microscopy.. bioRxiv.
2019
David AF, Roudot P, Legant WR, Betzig E, Danuser G, Gerlich DW.  2019.  Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth.. Journal of Cell Biology. 218(7):2150-68.
Colin-York H, Li D, Korobchevskaya K, Chang VT, Betzig E, Eggeling C, Fritzsche M.  2019.  Cytoskeletal actin patterns shape mast cell activation.. Communications Biology. 2:93.
Colin-York H, Javanmardi Y, Skamrahl M, Kumari S, Chang VT, Khuon S, Taylor A, Chew T-L, Betzig E, Moeendarbary E et al..  2019.  Cytoskeletal control of antigen-dependent T cell activation.. Cell Reports. 26(12):3369-3379.e5.
Turcotte R, Liang Y, Tanimoto M, Zhang Q, Li Z, Koyama M, Betzig E, Ji N.  2019.  Dynamic super-resolution structured illumination imaging in the living brain.. Proceedings of the National Academy of Sciences of the United States of America. 116(19):9586-91.
Pamula MC, Carlini L, Forth S, Verma P, Suresh S, Legant WR, Khodjakov A, Betzig E, Kapoor TM.  2019.  High-resolution imaging reveals how the spindle midzone impacts chromosome movement.. The Journal of Cell Biology. 218(8):2529-44.
O’Shaughnessy EC, Stone OJ, LaFosse PK, Azoitei ML, Tsygankov D, Heddleston JM, Legant WR, Wittchen ES, Burridge K, Elston TC et al..  2019.  Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor.. The Journal of Cell Biology. 218(9):3153-3160.
2018
Schöneberg J, Dambournet D, Liu T-L, Forster R, Hockemeyer D, Betzig E, Drubin DG.  2018.  4D cell biology: big data image analytics and lattice light-sheet imaging reveal dynamics of clathrin-mediated endocytosis in stem cell derived intestinal organoids.. Molecular Biology of the Cell. :mbcE18060375.
Swinburne IA, Mosaliganti KR, Upadhyayula S, Liu T-L, Hildebrand DGC, Tsai TY-C, Chen A, Al-Obeidi E, Fass AK, Malhotra S et al..  2018.  Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure.. eLife. 7